食品科学 ›› 0, Vol. ›› Issue (): 0-0.

• 食品化学 •    下一篇

包覆花色苷W/O/W型乳液的消化特性及其缓释效果

徐伟丽,张玉琪,朱元昊,鲁兆新,鲁兆新   

  1. 哈尔滨工业大学
  • 收稿日期:2019-05-06 修回日期:2020-02-17 出版日期:2020-05-25 发布日期:2020-05-15
  • 通讯作者: 徐伟丽 E-mail:weilixu698@163.com
  • 基金资助:
    基于Wnt/β-catenin信号通路的γ-生育三烯酚诱导成骨细胞分化的机制研究

Research on the digestion properties and controlled release of anthocyanins-loading water-in-oil-in-water double emulsions stabilized by PGPR and casein sodium

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  • Received:2019-05-06 Revised:2020-02-17 Online:2020-05-25 Published:2020-05-15
  • Supported by:
    γ-Tocotrienol induces osteoblastdifferentiation via the Wnt/β-catenin signaling pathway

摘要: 本文研究了体外消化对包埋葡萄皮花色苷(ACNs)的W/O/W型乳液控释和抗氧化性能的影响。W1/O/W2型乳液粒径为149.33±1.44 nm,并呈单峰分布,ACNs的包封率为82.99±2.38%。体外口腔消化对W1/O/W2型乳液液滴结构无明显影响。经口进入模拟胃消化后,因蛋白质水解W/O/W型乳液失去双层结构,释放的W1/O液滴因聚集在一起而使粒径(d=3830.33±1669.25 nm)显著增加(P<0.05)。经胃进入模拟肠道消化后,W1/O液滴破碎,平均粒径(d<150 nm)显著减小(P<0.05),此时具有最高的抗氧化活性。结果表明,W1/O/W2型乳液能有效地保护ACNs免受体外口腔和胃消化的影响,并可靶向地在模拟小肠内传递和释放。

关键词: 花色苷, W/O/W型乳液, 控制释放, 体外消化, 酪蛋白钠

Abstract: The effects of in vitro gastrointestinal digestion on the controlled release and antioxidant properties of encapsulated anthocyanins (ACNs) from grape skin in water-in-oil-in-water (W/O/W) double emulsions were determined. The double emulsions exhibited the monomodal distribution (d = 149.33 ± 1.44 nm) showing relatively high encapsulation efficiency (82.99 ± 2.38%). The in vitro mouth digestion did not affect the structure of the emulsion droplets. After the simulated gastric digestion, the double W1/O/W2 emulsions became a single W1/O emulsion due to proteolysis, which were aggregated together with significant increases (p<0.05) of average droplet sizes (d = 3830.33 ± 1669.25 nm). During intestinal digestion, W1/O droplets were broken, and the average droplet sizes (d<150 nm) decreased significantly (p<0.05), and the highest antioxidant activities were identified. Our results indicated that ACNs were effectively protected by W1/O/W2 double emulsions against in vitro mouth and gastric digestion, and were targetedly delivered in the simulated small intestine.

Key words: anthocyanins, W/O/W double emulsions, controlled release, in vitro digestion, casein sodium

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