食品科学 ›› 2020, Vol. 41 ›› Issue (11): 259-266.doi: 10.7506/spkx1002-6630-20190606-071

• 专题论述 • 上一篇    下一篇

辣椒红素的生物利用度、生理功能及机制研究进展

黎智华,王恬   

  1. (南京农业大学动物科技学院,江苏 南京 210095)
  • 出版日期:2020-06-15 发布日期:2020-06-22
  • 基金资助:
    “十三五”国家重点研发计划重点专项(2018YFD0501101)

Progress in Understanding the Bioavailability, Physiological Functions and Mechanisms of Action of Capsanthin

LI Zhihua, WANG Tian   

  1. (College of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China)
  • Online:2020-06-15 Published:2020-06-22

摘要: 辣椒红素是从成熟红辣椒中提取的一种类胡萝卜素,其色泽鲜艳、安全性高,被人们广泛用作于食品和饲料添加剂。辣椒红素是极性脂溶性物质,其生物利用度高于β-胡萝卜素。除了作为着色剂,辣椒红素还具有良好的抗氧化能力,能够清除体内过量的活性氧、参与调控与活性氧相关信号转导途径,从而缓解氧化应激对机体组织和细胞重要成分如脱氧核糖核酸、脂类和蛋白质的损伤,发挥广泛的生物学效应。以往研究发现,辣椒红素能够调节机体脂代谢、调节免疫、抗癌、抗辐射和减轻老年学习障碍,尤其是降低某些心血管疾病和癌症等慢性疾病的发病率。本文对近年来辣椒红素的生物利用度、生理功能及其作用机制进行了综述,以期为辣椒红素的功能性研究提供参考。

关键词: 辣椒红素, 生物利用度, 抗氧化, 脂代谢

Abstract: Capsanthin is a carotenoid compound extracted from mature red chili peppers. It is widely used as a food and feed additive because of bright color and high safety. Capsanthin, a polar lipid-soluble substance, has bioavailability better than that of β-carotene. Besides being a colorant, capsanthin has good antioxidant capacity. It can remove excess active oxygen species in the body and participate in the regulation of signal transduction pathways related to active oxygen species, therefore alleviating oxidative stress-induced damage to body tissues and important cellular components such as deoxyribonucleic acid, lipids and proteins and exerting a wide range of biological effects. Previous studies have found that capsanthin can regulate lipid metabolism in the body, modulate immune responses, has anti-cancer and anti-radiation effects, enhance learning ability in the elderly, and especially reduce the incidence of certain cardiovascular diseases, cancers and other chronic diseases. In this article, the advances made in understanding the bioavailability, physiological functions and mechanisms of action of capsanthin in recent years are reviewed, in order to provide a reference for studying the functional properties of capsanthin.

Key words: capsanthin, bioavailability, antioxidant activity, lipid metabolism

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