食品科学 ›› 2010, Vol. 31 ›› Issue (11): 241-243.doi: 10.7506/spkx1002-6630-201011052

• 营养卫生 • 上一篇    下一篇

江蓠藻膳食纤维降血脂作用研究

肖美添,叶 静,汤须崇   

  1. 华侨大学化工与制药工程系
  • 收稿日期:2009-09-29 出版日期:2010-06-01 发布日期:2010-12-29
  • 通讯作者: 肖美添 E-mail:mtxiao@hqu.edu.cn
  • 基金资助:

    福建省科技计划重点项目(2008N0120);泉州市科技计划重点项目(2008G06;2009N10)

Hypolipidemic Effect of Dietary Fibers from Gracilaria sp. in Hyperlipidemic Mice

XIAO Mei-tian,YE Jing,TANG Xu-chong   

  1. Department of Chemical and Pharmaceutical Engineering, Huaqiao University, Xiamen 361021, China
  • Received:2009-09-29 Online:2010-06-01 Published:2010-12-29
  • Contact: XIAO Mei-tian E-mail:mtxiao@hqu.edu.cn

摘要:

采用高脂饲料喂养昆明小鼠建立高脂血症模型,以燕麦膳食纤维为阳性对照,测定江蓠藻膳食纤维100、200、400mg/(kg bw·d)剂量灌胃给药高脂血症模型小鼠,4 周后对其总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)的影响。结果表明:江蓠藻膳食纤维能显著降低高血脂模型小鼠血清中TC、TG、LDL-C 的含量,降低肝脏脂质水平,同时升高血清HDL-C 含量。江蓠藻膳食纤维具有调节脂质代谢的作用,可降低高脂膳食导致的氧化损伤。

关键词: 江蓠藻, 膳食纤维, 降血脂

Abstract:

Kingming mice were fed high fat diet to establish a hyperlipidemic model. In order to explore the hypolipidemic effect of dietary fibers from Gracilaria sp. (GDF), the mice with hyperlipemia were administered GDF at the dosages of 100, 200 mg/(kg bw·d) and 400 mg/(kg bw·d) for 4 consecutive weeks. Oat dietary fiber was used as the control. Blood lipid indicators including total cholesterol (TC), triglyceride (TG), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C) were determined. GDF could significantly reduce the contents of TC, TG and LDL-C, and increase the content of HDL-C in serum. Therefore, GDF has the potential to regulate lipid metabolism and relieve oxidative injury induced by high fat diet.

Key words: Gracilaria sp., dietary fiber, hyperlipemia

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