FOOD SCIENCE ›› 2020, Vol. 41 ›› Issue (18): 134-139.doi: 10.7506/spkx1002-6630-20190802-037

• Bioengineering • Previous Articles     Next Articles

Relationship between the Signal Molecule N-Tetradecanoyl-L-homoserine lactone in Cnterobacter sakazakii and Its Growth

YAN Xiaotong, LUO Xiaojuan, PAN Jieru, YE Haimei, LIN Kan, LI Changcheng, FANG Ting   

  1. (1. School of Food Science, Fujian Agriculture and Forestry University, Fuzhou 350002, China;2. Fuzhou Center for Disease Control and Prevention, Fuzhou 350004, China)
  • Online:2020-09-25 Published:2020-09-18

Abstract: In this paper, the change in the concentration of the signal molecule N-tetradecanoyl-L-homoserine lactone (C14-HSL) during the growth process of Cnterobacter sakazakii CICC21550 at 37 ℃ was fitted to a curve. Based on the macroscopic model of bacterial growth, the growth mechanism of C. sakazakii CICC21550 was further explored from the microscopic perspective. The results showed that C14-HSL was detected in C. akazakii CICC21550 at the early logarithmic phase of growth, which reached the maximum value in the stationary period of bacterial growth, and then showed a gradually declining trend and it was in an obvious density-dependence manner. The maximum concentration Ymax of C14-HSL was 8.535 and the maximum rate of formation μmax was 0.825.

Key words: Cronobacter sakazakii; signal molecules; prediction model; Integrated Pathogen Modeling Program (IPMP)

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