FOOD SCIENCE ›› 2020, Vol. 41 ›› Issue (15): 295-300.doi: 10.7506/spkx1002-6630-20200301-001

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Recent Advances in miRNA and Functional Foods against Ionizing Radiation

LU Jike, CHEN Pei, CAO Nana, CHEN Chen, YI Juanjuan, HAO Limin   

  1. (1. School of Life Sciences, Zhengzhou University, Zhengzhou 450001, China; 2. The Quartermaster Research Institute of Engineering and Technology, Academy of Military Sciences People’s Liberation Army China, Beijing 100010, China)
  • Online:2020-08-15 Published:2020-08-19

Abstract: Consumption of functional foods against radiation is an effective way to protect against ionizing radiation damage. MicroRNAs (miRNAs) are endogenous non-coding RNAs regulating gene expression found in many eukaryotic organisms, and they are closely related to radiation protection. Food intake is a way of exchanging material, energy and information between organisms and the environment. Specific diets, including functional food factors, can affect the expression of miRNAs, and this effect may be transgenerational. MicroRNA-34a (miR-34a) plays an important role in protection against ionizing radiation, and the relationship between the signal pathway of miR-34a/Sirt1/p53 and functional foods against radiation deserves concern and needs to be further studied.

Key words: ionizing radiation, miRNAs, radiation protection, radioprotectants, functional foods

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