FOOD SCIENCE ›› 2019, Vol. 40 ›› Issue (13): 334-339.doi: 10.7506/spkx1002-6630-20180615-331

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Recent Progress in Rapid Screening Methods for Antibacterial Peptides

XUE Hui, TU Yonggang, XIONG Chunhong, LI Jianke, LUO Wenxiang, ZHAO Yan   

  1. 1. Engineering Research Center of Biomass Conversion, Ministry of Education, State Key Laboratory of Food Science and Technology, Nanchang University, Nanchang 330047, China; 2. College of Food Science and Engineering, Jiangxi Agricultural University, Nanchang 330045, China
  • Online:2019-07-15 Published:2019-07-23

Abstract: Antimicrobial peptides are a class of special bioactive peptides with broad-spectrum antibacterial activities, and are extensively applied in medicine, food, agriculture and other fields. This paper summarizes the applicability and characteristics of various pretreatment methods for detection of antibacterial peptides in crude samples. Emphasis is placed on the rapid screening methods for antimicrobial peptides, including bacterial adsorption method, cell membrane affinity chromatography, simulated cell membrane affinity chromatography, capillary electrophoresis, thin layer chromatography autoradiography and high throughput sequencing. This review will provide useful information for discovering new antimicrobial peptides and enriching the existing bank of antimicrobial peptides.

Key words: antimicrobial peptides, antibacterial, rapid screening, preparation

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