Optimization of Preparation of Collagen Polypeptide Chelated Calcium by Orthogonal Array Design

doi:10.7506/spkx1002-6630-201308019

Abstract

Abstract: This work reports the application of orthogonal array design to explore the optimum chelating conditions of food-grade calciumchloride with collagen polypeptide. The optimal chelating conditions were found to be reaction at 30℃ and an initial pH of 6.0 for 30 min with a calcium-to-collagen polypeptide mass ratio of 13:100. Under the optimized conditions, the calcium-chelating efficiency of collagen polypeptides was 77.7 mg/g. FTIR analysis demonstrated that we successfully obtained collagen polypeptide chelated calcium as a new material. Moreover, the chelated calcium was found to increase bone density in animal studies.

Key words: collagen polypeptide, chelating rate, bone calcium, bone mineral density

CLC Number:

TS218

PENG Qiao-yun，SHEN Ju-quan，WEI Dong-zhi，MA Zhi-ying，SHEN Ya-ling. Optimization of Preparation of Collagen Polypeptide Chelated Calcium by Orthogonal Array Design[J]. FOOD SCIENCE, 2013, 34(8): 94-99.

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