Determination of Perfluorooctanoic Acid and Perfluorooctane Sulphonic Acid in Foods of Animal Origin Using Polyamide Solid-Phase Extraction

Abstract

Abstract:

A method for the extraction of perfluorooctanoic acid (PFOA) and perfluorooctane sulphonic acid (PFOS) in
foods of animal origin using polyamide solid-phase extraction (SPE) was developed. Samples were extracted with acidified
acetonitrile, cleaned up and enriched on a polyamide SPE cartridge under acidic conditions through elution with 5%
ammonia-methanol and determined by ultra performance liquid chromatography-tandem mass spectrometry (UPLC-MS/
MS). The calibration curves for PFOA and PEOS exhibited good linearity (r = 0.9999) in the concentration range of 1 to 60
ng/mL, and the detection limit of the developed method was 0.2 μg/kg for both compounds and the average recovery rates
were in the range of 93.3% to 102.8% with relative standard deviations (RSD) of 0.8% to 6.2%.

Key words: ultra performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS), animal-origin food, perfluorooctanoic acid (PFOA), perfluorooctane sulphonic acid (PFOS), polyamide solid-phase extraction

CLC Number:

LIN Qin. Determination of Perfluorooctanoic Acid and Perfluorooctane Sulphonic Acid in Foods of Animal Origin Using Polyamide Solid-Phase Extraction[J]. FOOD SCIENCE, 2013, 34(10): 241-245.

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