FOOD SCIENCE ›› 2013, Vol. 34 ›› Issue (21): 311-314.doi: 10.7506/spkx1002-6630-201321062

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Flavonoids from Gnaphalium affine D. Don. Ameliorate Antioxidant Capacity in Diabetic Mice

  

  1. 1. College of Food Engineering, Xuzhou Institute of Technology, Xuzhou 221000, China;
    2. Jiangsu Key Construction Laboratory of Food Resource Development and Quality Safety, Xuzhou 221000, China
  • Received:2012-06-30 Revised:2013-09-16 Online:2013-11-15 Published:2013-10-28

Abstract:

The objective of this work was to study the biological activities of flavonoids from Gnaphalium affine D. Don.
in diabetic mice. Diabetic moue models were induced by intraperitoneal injection of streptozotocin. Changes in CAT, SOD,
GSH-Px, T-AOC and MDA content in the plasma and liver of mice were examined. Results showed that flavonoids from
Gnaphalium affine D. Don. were capable of improving antioxidant status in diabetic mice by enhancing the levels of SOD,
CAT, GSH-Px, and T-AOC with a reduced level of MDA. In summary, flavonoids from Gnaphalium affine D.Don. could
effectively ameliorate antioxidant status in diabetic mice.

Key words: flavonoids, diabetes, antioxidant

CLC Number: