The Extraction and Modification of Finger Citron Pectin and Its Prevention Effects to Cadmium Induced Liver and Kidney Injury

Abstract

Abstract: In this paper, the effects of chemical modification on the chemical properties and cadmium adsorption capacity of the pectin were studied. In addition, the cadmium adsorption capacity and adsorption process of pectin were analyzed by kinetic study and thermodynamics. Finally, a 20-day gavage experiment using ICR mice was performed to explore the prevention effect of pectin to cadmium-induced liver and kidney injury. The esterification degree of modified pectin was significantly lower than unmodified pectin. The modified pectin has stronger cadmium adsorption capacity than unmodified pectin. The process of the adsorption of cadmium by the pectin is mainly involved in the ion exchange process and physical adsorption process. In addition, finger citron pectin significantly alleviated the increased aspartate aminotransferase (AST), alanine aminotransferase (ALT), total bilirubin, γ-glutamyl transpeptidase (γGT), urea nitrogen, and creatinine in plasma, and urinary albumin level. In addition, the activities of superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx) in the liver and kidney of the mice in FCP/mFCP groups were significantly higher than those in the cadmium exposure group. Finger citron pectin significantly remitted the cadmium induced oxidative stress, and mitigated the effects of cadmium on the physiological function of liver and kidney. In conclusion, the chemical modification process reduces the esterification degree and enhances the cadmium adsorption capacity of the finger citron pectin. It can effectively relieve the cadmium induced liver and kidney injury.

Key words: finger citron peel residue pectin, ultrasonic-assisted acid extraction, modified pectin, cadimium adsorption, injury of liver and kidney

CLC Number:

R151.2

Sha-Ji WU Xing-Ran KOU Hongxin Wang. The Extraction and Modification of Finger Citron Pectin and Its Prevention Effects to Cadmium Induced Liver and Kidney Injury[J]. FOOD SCIENCE, 0, (): 0-0.

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