FOOD SCIENCE ›› 0, Vol. ›› Issue (): 0-0.

• Reviews •     Next Articles

Review on microbial biotransformation of EGCG and the bioactivities of its metabolites

  

  • Received:2019-04-18 Revised:2020-03-29 Online:2020-05-15 Published:2020-05-15

Abstract: Epigallocatechin gallate (EGCG), a polyphenolic flavonoid compound isolated from tea, habors many biological functions such as antioxidant, antibacterial and anti-tumor properties, lowering cholesterol levels and losing weight. However, its instability and low bioavailability lead to limited bioactivities. Recently, biotransformation mediated by microbes may provide an effective solution by modifying the structure of EGCG to improving its bioavailability while maintaining and even improving its original bioactivities. This review summarizes biotransformation of EGCG mediated by different microorganisms and the bioactivities of its breakdown products formed by microorganisms, mainly focusing on the metabolites, metabolic pathways and bioactivities of the metabolites, which provides a theoretical basis for the further study on the development of EGCG-related products with high extra value and human health promotion triggered by microbial biotransformation of polyphenols.

Key words: EGCG, biotransformation, microorganisms, metabolic pathways, biological activities

CLC Number: