Pyrrolizidine Alkaloids in Tea: A Review of Analytical Methods, Contamination Levels and Health Risk

Abstract

Abstract: Abstract：Pyrrolizidine alkaloids (PAs) are secondary metabolites of plants, among which 1,2-unsaturated pyrrolizidine alkaloids and most pyrrolizidine alkaloid N-oxides (PANOs) have multiple toxic effects. PAs have been found widely in various kinds of tea samples, and have become one of the main contaminants hindering the export of tea in China. This study reviewed the development of pretreatment methods and chromatographic-mass spectrometry detection techniques for PAs in tea and plant-derived samples, and looked forward to their development trends. The present review summarized the levels of PAs pollution in tea from different countries in recent years, and profiled the differences of PAs contaminated levels among tea types, as well as between tea and other food or agricultural products. Health risk of PAs in tea was evaluated based on the study of PAs toxicity. The data related to PAs pollution levels and risk assessment of tea in China are basically missing, so it is urgent to trace the resource of PAs pollution and risk assessment of tea.

Key words: pyrrolizidine Alkaloids, tea, analytical methods, contaminated levels, health risks

CLC Number:

O658

References

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