%0 Journal Article %A WANG Ya %A %A GAO Hongbo %A SUI Haixia %A QIU Kai %A ZHONG Qiding %A Lü Xiaoling %T Simultaneous Determination of 3-Monochloropropane-1,2-Diol Esters and Glycidyl Esters in Infant Formula Powder by Isotope Internal Standard-Gas Chromatography-Mass Spectrometry %D 2020 %R 10.7506/spkx1002-6630-20190326-335 %J FOOD SCIENCE %P 262-267 %V 41 %N 4 %X The aim of this study was the development of a method for the simultaneous determination of 3-monochloropropane-1,2-diol esters (3-MCPDEs) and glycidyl esters (GEs) in infant formula milk powder. Commercial infant formulas available on the Chinese market (n = 30) were analyzed for 3-MCPDEs and GEs by gas chromatography-mass spectrometry (GC-MS). Under the optimized conditions, 3-MCPDEs and GEs showed good linearity in the concentration range of 0.050?0.80 mg/L with correlation coefficient (R2) larger than 0.998. The mean recoveries from spiked samples were in the range of 81.4%?86.2% and 94.5%?101.1% with relative standard deviations (RSDs) ranging from 4.42% to 4.84% and from 4.46% to 6.12% for 3-MCPDEs and GEs, respectively. The limit of detection (LOD) of the proposed method was 30 μg/kg for both 3-MCPDEs and GEs. This method showed the advantages of high sensitivity, and accuracy, and could be suitable for the simultaneous detection of 3-MCPDEs and GEs in infant formula milk powder. In the 30 infant formula samples, levels of 3-MCPDEs and GEs ranged from 50.0 to 207.8 μg/kg and from 50.0 to 480.0 μg/kg with an average of 98.0 and 208.1 μg/kg, respectively. %U https://www.spkx.net.cn/EN/10.7506/spkx1002-6630-20190326-335