印度人参根提取物的免疫调节作用

食品科学 ›› 2008, Vol. 29 ›› Issue (7): 412-415.

印度人参根提取物的免疫调节作用

周才琼, 张雨

西南大学食品科学学院；西南大学食品科学学院重庆400716；重庆400716

出版日期:2008-07-15 发布日期:2011-07-28

Immunomodulatory Effect of Indian Ginseng Root Extract

ZHOU Cai-Qiong, ZHANG Yu

College of Food Science, Southwest University, Chongqing 400716, China

Online:2008-07-15 Published:2011-07-28

摘要/Abstract

摘要： 目的:研究引种新资源——印度人参根提取物免疫调节作用。方法:经口给予小鼠5、2.5、0.85g/kgbw印度人参根提取物,观察其对30d喂养小鼠免疫功能的影响。结果:印度人参根提取物对小鼠迟发型变态反应有促进作用,ConA诱导的脾淋巴细胞增殖能力明显增强;高、中剂量组溶血空斑数及巨噬细胞对鸡红细胞吞噬率、吞噬指数高于对照。各剂量组骨髓DNA含量高于对照,高、中剂量组血清NO含量明显高于对照(p<0.01),碱性磷酸酶和酸性磷酸酶活性只有高剂量组高于对照。结论:印度人参根提取物具有增强免疫功能作用。

关键词: 印度人参, 免疫作用, DNA含量, NO含量, 磷酸酶活性

Abstract: Objective: To study the immunemodulatory effect of Indian ginseng root extract (IGRE) growing in Chongqing. Methods: Mice were fed with IGRE at dose of 5, 2.5, 0.85 g/kg bw for 30 days, then their immune function were studied. Results: IRRE could stimulate response of delayed hypersensitivity. The proliferation of ConA-induced mitogenic reponse for spleen lymphocyte are also increased. Only in the high dose group and medium dose group the amount of hemolytic antibody in mice serum increases and the percentage as well as index of phagocytosis of celiac macrophage enhances compared with those of the control group mice. Further, marrow DNA content and serum NO content in all dose groups are higher than those of mice in the control group, while the activities of acid phosphatase and alkalinity phosphatase of mice serum only in the high dose group are higher than those of mice serum in the control group. Conclusion: Indian ginseng root extract can enhance immunce function of mice.

Key words: Indian ginseng, immune effect, DNA content, NO content, activity of phosphatase

周才琼, 张雨. 印度人参根提取物的免疫调节作用[J]. 食品科学, 2008, 29(7): 412-415.

ZHOU Cai-Qiong, ZHANG Yu. Immunomodulatory Effect of Indian Ginseng Root Extract[J]. FOOD SCIENCE, 2008, 29(7): 412-415.

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