Abstract: The research aimed to analyze and evaluate the nutrients of Anadara uropygimelana collected from Shandong, Liaoning and Jiangsu provinces. Analysis methods of nutrient components were based on the standards of GB 5009-2010 and AOAC 996.06. Evaluation standards of the nutritive quality were based on the FAO/WHO’s standard mode. The general nutrient compositions were determined with routine methods. Amino acid compositions were determined with amino acid analyzer. Fatty acid compositions were inspected with GC. The results showed that the protein contents and energy value of Jiangsu population were higher than those of other populations. There was the maximal content of carbohydrate 31 mg/g in wet weight in Liaoning population. All kinds of amino acids were found in Anadara uropygimelana. The total levels of amino acids in various populations were arranged in a descending order as the following: Shandong (719.75 mg/g) > Jiangsu (703.54 mg/g) > Liaoning (685.16 mg/g). The ratio of EAA/ TAA varied between 36.72 % - 34.91 % and the essential amino acid index of Shandong population was 61.21, which was the maximum one. The content of delicious amino acids was abundant varying between 276.92-293.21 mg/g. The content of ω-3 PUFA in fatty acids was high and also the content of vitamin and Ca, Fe, Zn, Se etc. were rich. Although the nutritive composition were different in edible part of Anadara uropygimelana from three provinces, Anadara uropygimelana is a seafood with high nutritional value and is good for health comparing with other marine bivalves.