Inhibitory Effect and Mechanisms of Sophorolipids against Staphyloccocus aureus

Abstract

Abstract: To explore antibacterial mechanisms of sophorolipids against Staphylococcus aureus, the minimum inhibitory concentration (MIC) of sophorolipids against S. aureus and the growth curves of S. aureus were determined. The microscopic structure of S. aureus was observed through scanning electron microscope (SEM) and transmission electron microscope (TEM). Results showed that sophorolipids effectively inhibited the growth of S.aureus. The inhibitory effect of sophorolipids was a concentration-depended mode, and the MIC of sophorolipids was 1.5625 mg/mL. However, the inhibitory effect of sophorolipids was stable at acid and high temperature condition, indicating that it had excellent stability. Furthermore, sophorolipids should pay antibacterial role through destroying cell membrane and cell wall according to SEM and TEM.

Key words: sophorolipids, antibacterial, MIC, scanning electron microscope (SEM), transmission electron microscope (TEM)

CLC Number:

Q935

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