Abstract:

This study was carried out to provide useful experimental evidences for the development of Pu’er tea-related products. Rotarod performance test, weight-loaded swimming test and liver glycogen determination were adopted for comparing anti-fatigue function of common Pu’er tea and compound Pu’er tea with American ginseng in mice. Totally 96 SPF ICR mice (18－22 g, half male and half female) were randomly divided into 8 groups of 12 mice each, namely blank control group, positive control group, three common Pu’er tea groups and three compound Pu’er tea with American ginseng groups. Positive control group was administrated by gavage with 200 mg/kg bw Panax notoginsenosides. High-, medium- and low-dose Pu’er tea and compound Pu’er tea with American ginseng were administered at 5.0, 2.5 g/kg bw and 1.25 g/kg bw, respectively. Mice administer with the same volume of water (20 mL/kg bw) were served as blank control group. All mice were administered once a day for continuously 14 days. Results showed that both medium and high doses of common Pu’er tea and compound Pu’er tea with American ginseng could significantly prolong the rotarod performance time in mice. In addition, different increases in weightloaded swimming time were observed in mice administered with both kinds of tea for continuously 14, and a big increase in mice administered with compound Pu’er tea with American ginseng. Furthermore, the two kinds of tea enhanced the static storage of liver glycogen to different extents.

Key words: compound Pu’er tea with American ginseng, anti-fatigue function, pharmacological study