Abstract: In order to study effects of chewable tablets of royal jelly on alleviating physical fatigue of mice, the mice were administered with the chewable tablets at the doses of 0.167, 0333 g/kg bw and 0.999 g/kg bw for 30 days by intragastric infusion, respectively. The results showed that the doses of 0.333 g/kg bw and 0.999 g/kg bw can significantly decrease the level of mice serum urea after movement. The dose of 0.999 g/kg bw can prolong the weight loading swimming time, significantly decreased the area behind mice blood lactate curve (p<0.05 or p<0.01) and have no obvious effect on storage quantity of hepatic glycogen (p>0.05). So it is concluded that the chewable tablets of royal jelly can alleviate physical fatigue of mice.

Key words: chewable tablets of royal jelly, alleviate, physical fatigue