Abstract: Flavonoids of Artemisia argyi (FAA) were investigated for their radical scavenging activity in vitro by using four chemiluminescence systems. The results showed that FAA can effectively scavenge O2-·,·OH and H2O2,and reduce or prevent DNA oxidative damage caused by ·OH. The 50% inhibition concentrations(IC50) are 151.17,15.34,0.23 and 15.46 mg/L. Compared with VC,FAA have higher antioxidant activity are effective and multifunctional natural antioxidants and radical scavengers,and are worth further exploiting and utilizing.

Key words: flavonoids of Artemisia argy, iantioxidant activity in vitro, chemiluminescence methods, protection effect on DNA damage