Abstract: The aim of this study was to assess the anti-halitosis effect of water soluble propolis(WSP) through its inhibiory effect against halitosis-correlated bacteria. The possibility of WSP as a new materal for preventing halitosis was explored. Porphyromonas gingivalis,Prevotella intermedia and Fusobacterium nucleatum were chosen as the experimental bacteria. The minimal inhibitory concentration(MIC) of WSP was tested through minute amount serial dilution test. The results showed that WSP could inhibit all experimental bacteria. It is effective for inhibiting halitosis-correlated bacteria in vitro.

Key words: water soluble propolis, halitosis, halitosis-correlated bacteria