Abstract: Agaricus blazei Murill was a delicious medicinal fungus. In this paper, the submerged fermetation process and amino analysis of the strain were studied . Experimental results showed that the composition of the optimal fermentation medium was as fellows: 7%lucose, 1. 5% yeast extract, 0. 3%K2HPO4, 0. 1%MgSO4and 10mg/100mlVB1. The optimum cultural period was 9 days at 25℃ in 250ml flasks shaked at 150r/min. Thebest aeration ratio was 2: 5 (medium volome: flask volume). The inoculation size was 15% . The dry weight of mycelia of Agaricus blazei Murill was obtained about 1. 8g /100ml in the optium culture.

Key words: Agaricus blazei , Murill Submerge Cultivates mycelium