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Research Progress in Anticancer Effect of Cyanidin-3-glucoside

CHEN Liang1,2,XIN Xiu-lan2,YUAN Qi-peng1,*   

  1. 1. State Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology, Beijing 100029, China;
    2. College of Bioengineering, Beijing Polytechnic, Beijing 100029, China
  • Online:2013-07-15 Published:2013-06-28
  • Contact: YUAN Qi-peng

Abstract:

Anthocyanins are a group of naturally occurring flavonoid compounds, which is widely available in fruits
and vegetables in human diets. A lot of epidemiological and animal experiments have demonstrated that anthocyanins
may contribute to cancer chemoprevention. In this article, we summarize the anti-cancer effects and the mechanisms of
anthocyanins and cyanidin-3-glucoside (C3G) in berries and related food products on several key steps: antioxidant effects,
enzyme activation, anti-cell proliferation, apoptosis induction, anti-inflammation, anti-angiogenesis, anti-invasiveness,
and differentiation induction. This review provides a molecular view of cyanidin-3-glucoside contributing to cancer
chemoprevention.

Key words: anthocyanins, cyanidin-3-glucoside, anti-cancer effect

CLC Number: