Research Progress in Molecular Mechanisms of Caffeic Acid and Its Derivatives on Anti-tumor Function

doi:10.7506/spkx1002-6630-201319070

Abstract

Abstract:

Caffeic acid and its derivatives (CADs) are widely spread in the daily foods/meals, and play an important role in
the suppression of tumor cell growth, differentiation, proliferation and transfer process. This article reviews the molecular
mechanisms such as the effects of CADs on tumor suppression through oxidative stress, signaling pathways and transcription
factors, epithelial-mesenchymal transition, cancer stem cell-like properties, and epigenetic regulation in order to provide a
reference for health-promoting function of active components in food and dietary intervention.

Key words: caffeic acid derivatives, anti-tumor, molecular mechanisms

CLC Number:

TS201.24

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Research Progress in Molecular Mechanisms of Caffeic Acid and Its Derivatives on Anti-tumor Function

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