Abstract: Flavonoids are a wide variety of secondary plant metabolites with complex structures that widely exist in plant roots, stems, leaves, flowers and fruits. These compounds have attracted much attention due to their greatly positive effects on human health, such as anticancer, antibacterial, anti-viral, anti-inflammatory and anti-allergic. Researchers have verified their various biological activities in vivo and in vitro. However, flavonoids usually coexist with other compounds in plants, such as carbohydrate, protein, lipid and acid, and interact with these compounds inside the body when ingested together. Therefore, the functions of flavonoids have a close relationship with other compounds. The interaction between flavonoids and other compounds together with the underlying mechanisms and the outcome is reviewed in this paper.

Key words: flavonoids, carbohydrate, protein, lipid, acid, interaction