FOOD SCIENCE ›› 0, Vol. ›› Issue (): 0-0.
• Reviews • Next Articles
1,Xue-Li LI1, 1, 1,Yan-Rong GUO1, 1,Meng-Xuan LAIHairan Ma
Received:
2022-12-29
Revised:
2023-11-03
Online:
2024-01-15
Published:
2024-02-02
Contact:
Hairan Ma
E-mail:mahairan@mengniu.cn
CLC Number:
Xue-Li LI Yan-Rong GUO Meng-Xuan LAI Hairan Ma. Research progress and application status of postbiotics[J]. FOOD SCIENCE, 0, (): 0-0.
[1]赵烜影, 杨扬, 王国骄, 等.后生元及其在乳制品中的应用研究进展[J].乳业科学与技术, 2022, 45(02):47-54 [2]王炜哲, 翟征远, 郝彦玲.市售酸奶中发酵剂乳酸菌的耐药性及耐药基因研究进展[J].中国乳品工业, 2022, 50(02):34-37 [3]许女, 贾瑞娟, 李雅茹, 等.老陈醋来源乳酸菌的益生特性筛选及安全评价[J].中国食品学报, 2020, 20(10):23-33 [4]中国食品科学技术学会益生菌分会.后生元的研究现状及产业应用[J].中国食品学报, 2022, 22(08):416-426 [5]Salminen S, Collado M C, Endo A, et al.The International Scientific Association of Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of postbiotics[J].Nature reviews. Gastroenterology & hepatology, 2021, 18(9):649-667 [6]李杨, 周湘人, 郭薇丹, 等.后生元的研究进展[J].食品安全质量检测学报, 2021, 12(16):6558-6564 [7]白娜, 李周勇, 康小红.后生元的研究进展[J].食品科技, 2022, 47(01):20-25 [8]王岩, 杨彩梅, 胡爱心, 等.后生元的益生机制及其在动物生产中的应用前景[J].中国畜牧杂志, 2022, 58(06):73-78 [9]Ou C C, Lin S L, Tsai J J, et al.Heat-killed lactic acid bacteria enhance immunomodulatory potential by skewing the immune response toward Th1 polarization[J].J Food Sci, 2011, 76(5):M260-M267 [10]Chung I C, OuYang C N, Yuan S N, et al.Pretreatment with a Heat-Killed Probiotic Modulates the NLRP3 Inflammasome and Attenuates Colitis-Associated Colorectal Cancer in Mice[J].Nutrients, 2019, 11(3):1-16 [11]Antoni C, Josep M D B, Noemí B, et al.Heat-killed Bifidobacterium animalis subsp. Lactis CECT 8145 increases lean mass and ameliorates metabolic syndrome in cafeteria-fed obese rats[J].Journal of Functional Foods, 2017, 38:251-263 [12]Lin W Y, Kuo Y W, Chen C W, et al.Viable and Heat-Killed Probiotic Strains Improve Oral Immunity by Elevating the IgA Concentration in the Oral Mucosa[J].Curr Microbiol, 2021, 78(9):3541-3549 [13]Jhong J H, Tsai W H, Yang L C, et al.Heat-Killed Lacticaseibacillus paracasei GMNL-653 Exerts Antiosteoporotic Effects by Restoring the Gut Microbiota Dysbiosis in Ovariectomized Mice[J].Front Nutr, 2022, 9:804210-804231 [14]Nishida K, Sawada D, Kuwano Y, et al.Health Benefits of Lactobacillus gasseri CP2305 Tablets in Young Adults Exposed to Chronic Stress: A Randomized, Double-Blind, Placebo-Controlled Study[J].Nutrients, 2019, 11(8):1859-1873 [15]刘颖, 张欢, 牛超杰, 等.后生元的开发与应用研究新趋势[J].武汉轻工大学学报, 2021, 40(05):14-20 [16]Ahn J E, Kim H, Chung D K.Lipoteichoic Acid Isolated from Lactobacillus plantarum Maintains Inflammatory Homeostasis through Regulation of Th1- and Th2-Induced Cytokines[J].J Microbiol Biotechnol, 2019, 29(1):151-159 [17]Noh S Y, Kang S S, Yun C H, et al.Lipoteichoic acid from Lactobacillus plantarum inhibits Pam2CSK4-induced IL-8 production in human intestinal epithelial cells[J].Mol Immunol, 2015, 64(1):183-189 [18]Friedrich A D, Leoni J, Paz M L, et al.Lipoteichoic Acid from Lacticaseibacillus rhamnosus GG Modulates Dendritic Cells and T Cells in the Gut[J].Nutrients, 2022, 14(3):723-738 [19]Balaguer F, Enrique M, Llopis S, et al.Lipoteichoic acid from Bifidobacterium animalis subsplactis BPL1: a novel postbiotic that reduces fat deposition via IGF-1 pathway[J].Microb Biotechnol, 2022, 15(3):805-816 [20]Hu C C, Chang C H, Hsiao Y M, et al.Lipoteichoic Acid Accelerates Bone Healing by Enhancing Osteoblast Differentiation and Inhibiting Osteoclast Activation in a Mouse Model of Femoral Defects[J].Int J Mol Sci, 2020, 21(15):5550-5563 [21]Kim K W, Kang S S, Woo S J, et al.Lipoteichoic Acid of Probiotic Lactobacillus plantarum Attenuates Poly I:C-Induced IL-8 Production in Porcine Intestinal Epithelial Cells[J].Front Microbiol, 2017, 8:1827-1835 [22]Wolf A J, Underhill D M.Peptidoglycan recognition by the innate immune system[J].Nat Rev Immunol, 2018, 18(4):243-254 [23]Jing Y, Ran Y, Zhao J, et al.Peptidoglycan Suppresses Phagocytic Activities and Apoptosis of Macrophages in Colonic Mucosa Tissues of Crohn' s Disease Patients and In Vitro[J].Med Sci Monit, 2018, 24:3382-3392 [24]Li X, Sun Q, Wang Y, et al.The regulatory effects of Lplantarum peptidoglycan microspheres on innate and humoral immunity in mouse[J].J Microencapsul, 2017, 34(7):635-643 [25]兰冬雪, 瞿茜楠, 黄天, 等.益生菌活性代谢产物的研究及应用进展[J].食品工业科技, 2022, 43(24):11-20 [26]王俊永, 姚蒙蒙, 王晓冰, 等.益生菌胞外多糖的生物活性研究进展[J].饲料工业, 2020, 41(22):9-11 [27]姜云芸, 刘红霞, 李洪亮, 等.鼠李糖乳杆菌胞外多糖的研究进展[J].中国食品添加剂, 2020, 31(10):135-140 [28]Li W, Ji J, Chen X, et al.Structural elucidation and antioxidant activities of exopolysaccharides from Lactobacillus helveticus MB2-1[J].Carbohydr Polym, 2014, 102:351-359 [29]黄蓉, 张学亮, 韩烁, 等.瑞士乳杆菌-源胞外多糖对种益生菌生长特性的影响[J].食品科学, 2020, 41(06):163-169 [30]Del P M, Balzarini M, Carmagnola S, et al.Assessment of the capability of a gelling complex made of tara gum and the exopolysaccharides produced by the microorganism Streptococcus thermophilus ST10 to prospectively restore the gut physiological barrier: a pilot study[J].J Clin Gastroenterol, 2014, 48(Suppl 1):S56-S61 [31]Noda M, Kanno K, Danshiitsoodol N, et al.Plant-Derived Lactobacillus paracasei IJH-SONE68 Improves Chronic Allergy Status: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial[J].Nutrients, 2021, 13(11):4022-4033 [32]Wallimann A, Magrath W, Thompson K, et al.Gut microbial-derived short-chain fatty acids and bone: a potential role in fracture healing[J].Eur Cell Mater, 2021, 41:454-470 [33]毛慧芳, 梁永林.A.muciniphila及其代谢物短链脂肪酸与溃疡性结肠炎肠黏膜屏障的相关性研究[J].微生物学报, 2022, :1-22 [34]Lucas S, Omata Y, Hofmann J, et al.Short-chain fatty acids regulate systemic bone mass and protect from pathological bone loss[J].Nat Commun, 2018, 9(1):55-64 [35]蔡巧利, 陈晓雯, 宋翔, 等.益生菌对肠道黏膜屏障的影响[J].饲料研究, 2022, 45(13):141-144 [36]Yan F, Cao H, Cover T L, et al.Colon-specific delivery of a probiotic-derived soluble protein ameliorates intestinal inflammation in mice through an EGFR-dependent mechanism[J].J Clin Invest, 2011, 121(6):2242-2253 [37]Bauerl C, Perez-Martinez G, Yan F, et al.Functional analysis of the p40 and p75 proteins from Lactobacillus casei BL23[J].J Mol Microbiol Biotechnol, 2010, 19(4):231-241 [38]Hevia A, Martinez N, Ladero V, et al.An extracellular SerineThreonine-rich protein from Lactobacillus plantarum NCIMB 8826 is a novel aggregation-promoting factor with affinity to mucin[J].Appl Environ Microbiol, 2013, 79(19):6059-6066 [39]Godwin J W, Pinto A R, Rosenthal N A.Chasing the recipe for a pro-regenerative immune system[J].Semin Cell Dev Biol, 2017, 61:71-79 [40]高杰, 何肖龙, 曹虹.后生元:调节肝硬化患者肠道菌群及疾病进程的新策略[J].微生物学报, 2018, 58(11):1938-1949 [41]康宇鸿, 何剑, 赵六永, 等.含有后生元和β-葡聚糖的乳饮料对小鼠免疫功能的影响[J].中国乳品工业, 2022, 50(01):14-18 [42]任亚雪, 郭乾鹏, 李媛媛, 等.屎肠球菌活菌和热灭活菌对细胞肿瘤坏死因子-α白细胞介素-平衡以及丝裂原活化蛋白激酶信号通路的影响[J].动物营养学报, 2020, 32(09):4345-4357 [43]Jeong M, Kim J H, Lee J S, et al.Heat-Killed Lactobacillus brevis Enhances Phagocytic Activity and Generates Immune-Stimulatory Effects through Activating the TAK1 Pathway[J].J Microbiol Biotechnol, 2020, 30(9):1395-1403 [44]Maehata H, Arai S, Iwabuchi N, et al.Immuno-modulation by heat-killed Lacticaseibacillus paracasei MCC1849 and its application to food products[J].Int J Immunopathol Pharmacol, 2021, 35:1-9 [45]Rocha-Ramirez L M, Hernandez-Ochoa B, Gomez-Manzo S, et al.Impact of Heat-Killed Lactobacillus casei Strain IMAU60214 on the Immune Function of Macrophages in Malnourished Children[J].Nutrients, 2020, 12(8):2303-2319 [46]Jung Y J, Kim K H, Ko E J, et al.Adjuvant effects of killed Lactobacillus casei DK128 on enhancing T helper type 1 immune responses and the efficacy of influenza vaccination in normal and CD4-deficient mice[J].Vaccine, 2020, 38(36):5783-5792 [47]Nakai H, Murosaki S, Yamamoto Y, et al.Safety and efficacy of using heat-killed Lactobacillus plantarum L-137: High-dose and long-term use effects on immune-related safety and intestinal bacterial flora[J].J Immunotoxicol, 2021, 18(1):127-135 [48]Lee J, Jung I, Choi J W, et al.Micronized and Heat-Treated Lactobacillus plantarum LM1004 Stimulates Host Immune Responses Via the TLR-2MAPKNF-kappaB Signalling Pathway In Vitro and In Vivo[J].J Microbiol Biotechnol, 2019, 29(5):704-712 [49]Jorjao A L, de Oliveira F E, Leao M V, et al.Live and Heat-Killed Lactobacillus rhamnosus ATCC 7469 May Induce Modulatory Cytokines Profiles on Macrophages RAW 264.7[J].ScientificWorldJournal, 2015, 2015:716749-716754 [50]Pique N, Berlanga M, Minana-Galbis D.Health Benefits of Heat-Killed (Tyndallized) Probiotics: An Overview[J].Int J Mol Sci, 2019, 20(10):2534-2563 [51]Groschwitz K R, Hogan S P.Intestinal barrier function: molecular regulation and disease pathogenesis[J].J Allergy Clin Immunol, 2009, 124(1):3-20 [52]Montalto M, Maggiano N, Ricci R, et al.Lactobacillus acidophilus protects tight junctions from aspirin damage in HT-29 cells[J].Digestion, 2004, 69(4):225-228 [53]Sakai Y, Arie H, Ni Y, et al.Lactobacillus pentosus strain S-PT84 improves steatohepatitis by maintaining gut permeability[J].J Endocrinol, 2020, 247(2):169-181 [54]Zeng Y, Zhang H, Tsao R, et al.Lactobacillus pentosus S-PT84 Prevents Low-Grade Chronic Inflammation-Associated Metabolic Disorders in a Lipopolysaccharide and High-Fat Diet C57BL6J Mouse Model[J].J Agric Food Chem, 2020, 68(15):4374-4386 [55]Forootan M, Bagheri N, Darvishi M.Chronic constipation: A review of literature[J].Medicine (Baltimore), 2018, 97(20):e10631-e10639 [56]陈建国, 李周勇, 李桂花, 等.热灭活副干酪乳杆菌Lc19对小鼠便秘的缓解作用研究[J].中国奶牛, 2019, 2019(09):12-15 [57]Bharucha A E, Wald A.Chronic Constipation[J].Mayo Clin Proc, 2019, 94(11):2340-2357 [58]Hara T, Mihara T, Ishibashi M, et al.Heat-killed Lactobacillus casei subsp. casei 327 promotes colonic serotonin synthesis in mice[J].Journal of Functional Foods, 2018, 47:585-589 [59]Sugawara T, Sawada D, Ishida Y, et al.Regulatory effect of paraprobiotic Lactobacillus gasseri CP2305 on gut environment and function[J].Microb Ecol Health Dis, 2016, 27:30259-30269 [60]Rad A H, Aghebati-Maleki L, Kafil H S, et al.Molecular mechanisms of postbiotics in colorectal cancer prevention and treatment[J].Crit Rev Food Sci Nutr, 2021, 61(11):1787-1803 [61]魏文培, 菅佳宁, 由凤鸣, 等.中医药调节结肠癌免疫功能的研究进展[J].中医肿瘤学杂志, 2021, 3(04):60-63 [62]Thakur B K, Saha P, Banik G, et al.Live and heat-killed probiotic Lactobacillus casei Lbs2 protects from experimental colitis through Toll-like receptor 2-dependent induction of T-regulatory response[J].Int Immunopharmacol, 2016, 36:39-50 [63]Kim S J, Kang C H, Kim G H, et al.Anti-Tumor Effects of Heat-Killed L. reuteri MG5346 and L. casei MG4584 against Human Colorectal Carcinoma through Caspase-9-Dependent Apoptosis in Xenograft Model[J].Microorganisms, 2022, 10(3):533-543 [64]汪玲娥, 庞立冬, 李誉, 等.后生元调节肥胖的研究进展[J].食品科学, 2022, :1-17 [65]Aoun A, Darwish F, Hamod N.The Influence of the Gut Microbiome on Obesity in Adults and the Role of Probiotics,Prebiotics,and Synbiotics for Weight Loss[J].Prev Nutr Food Sci, 2020, 25(2):113-123 [66]邓思思, 陈静, 刘雪, 等.嗜黏蛋白阿克曼菌及_对高脂饮食联合链脲佐菌素诱导的糖尿病大鼠的保护作用[J].四川大学学报医学版, 2022, 53(01):83-91 [67]Pedret A, Valls R M, Calderon-Perez L, et al.Effects of daily consumption of the probiotic Bifidobacterium animalis subsplactis CECT 8145 on anthropometric adiposity biomarkers in abdominally obese subjects: a randomized controlled trial[J].Int J Obes (Lond), 2019, 43(9):1863-1868 [68]Hsieh F C, Lan C C, Huang T Y, et al.Heat-killed and live Lactobacillus reuteri GMNL-263 exhibit similar effects on improving metabolic functions in high-fat diet-induced obese rats[J].Food Funct, 2016, 7(5):2374-2388 [69]赵隽隽, 乐科易, 冯希平, 等.嗜酸乳杆菌和青春双歧杆菌对牙周致病菌的拮抗作用[J].上海口腔医学, 2011, 20(04):364-367 [70]Karaca B, Yilmaz M, Gursoy U K.Targeting Nrf2 with Probiotics and Postbiotics in the Treatment of Periodontitis[J].Biomolecules, 2022, 12(5):729-742 [71]Lin C W, Chen Y T, Ho H H, et al.Impact of the food grade heat-killed probiotic and postbiotic oral lozenges in oral hygiene[J].Aging (Albany NY), 2022, 14(5):2221-2238 [72]丁琴凤, 马丽, 冯希平.嗜酸乳杆菌及其灭活菌粘附及拮抗牙周致病菌特性研究[J].现代口腔医学杂志, 2012, 26(06):378-382 [73]王琳琳, 李虎虎, 戴永娜.骨质疏松症流行病学与中药新药研发机遇研究[J].中国处方药, 2022, 20(09):1-4 [74]Bhardwaj A, Sapra L, Tiwari A, et al." Osteomicrobiology" : The Nexus Between Bone and Bugs[J].[J]. Front Microbiol, 2021, 12:812466. , 2021, 12:812446-812467 [75]Yeom J, Ma S, Lim Y H.Probiotic Propionibacterium freudenreichii MJ2 Enhances Osteoblast Differentiation and Mineralization by Increasing the OPG/RANKL Ratio[J].Microorganisms, 2021, 9(4):673-694 [76]Jang A R, Park J S, Kim D K, et al.Cell-free culture supernatant of Lactobacillus curvatus Wikim38 inhibits RANKL-induced osteoclast differentiation and ameliorates bone loss in ovariectomized mice[J].Lett Appl Microbiol, 2021, 73(3):383-391 [77]Montazeri-Najafabady N, Ghasemi Y, Dabbaghmanesh M H, et al.Exploring the bone sparing effects of postbiotics in the post-menopausal rat model[J].BMC Complement Med Ther, 2021, 21(1):155-166 [78]Sapra L, Dar H Y, Bhardwaj A, et al.Lactobacillus rhamnosus attenuates bone loss and maintains bone health by skewing Treg-Th17 cell balance in Ovx mice[J].Sci Rep, 2021, 11(1):1807-1824 [79]Toyoda A, Kawase T, Tsukahara T.Effects of dietary intake of heat-inactivated Lactobacillus gasseri CP2305 on stress-induced behavioral and molecular changes in a subchronic and mild social defeat stress mouse model[J].Biomed Res, 2020, 41(2):101-111 [80]Nishida K, Sawada D, Kawai T, et al.Para-psychobiotic Lactobacillus gasseri CP2305 ameliorates stress-related symptoms and sleep quality[J].J Appl Microbiol, 2017, 123(6):1561-1570 [81]Fujii T, Fujitomo T, Tsuji R, et al.Effects of Heat-Killed Lactococcus lactis Strain Plasma on Skin Homeostasis-Related Genes and the Skin Microbiome among Healthy Adults: A Randomized Controlled Double-Blind Study[J].Microorganisms, 2021, 9(10):2029-2044 [82]Jang H J, Song M W, Lee N K, et al.Antioxidant effects of live and heat-killed probiotic Lactobacillus plantarum Ln1 isolated from kimchi[J].J Food Sci Technol, 2018, 55(8):3174-3180 [83]王琦.日本后生元研究历史、现状及前景: 第十七届益生菌与健康国际研讨会, 中国浙江杭州, 2022[C]. DOI:10.26914/c.cnkihy.2022.018589 [84]陈建国, 程池, 伊地知哲生.日本灭活乳酸菌市场及其产品实例分析[J].食品与发酵工业, 2018, 44(06):300-302 [85]朱秀敏, 曹萌.灭活益生菌的研究进展[J].中国微生态学杂志, 2010, 22(02):175-17 |
[1] | LIU Hongxia, LI Xueli, WU Xiuying, Feng Xudong, Guo Yanrong, Jiang Yunyun, Lai Mengxuan, Ma Hairan. Progress on Research and Application of Postbiotics [J]. FOOD SCIENCE, 2024, 45(1): 326-333. |
[2] | LIAO Liuyue, ZHU Zhenzhu, YANG Qian, LIU Qin. Garlic-Derived Extracellular Nanovesicles: Bioactive Components and Their Roles in Alleviating Colitis in Mice [J]. FOOD SCIENCE, 2023, 44(7): 132-141. |
[3] | LIU Binshan, WEI Xiaoming, SHAO Danqing, DONG Zhizhong, LIU Yuping. Characterization of the Key Odorants in Shaomai and Their Changes during Storage by Gas Chromatography-Mass Spectrometry/Olfactometry Coupled with Odor Activity Value Calculation [J]. FOOD SCIENCE, 2023, 44(6): 268-276. |
[4] | LIANG Luodan, CAO Weiwei, LI Linlin, REN Guangyue, CHEN Junliang, XU Hanshan, DUAN Xu. Research Progress in Encapsulation of Bioactive Compounds in Protein-Polysaccharide Non-covalent and Covalent Complexes [J]. FOOD SCIENCE, 2023, 44(21): 368-385. |
[5] | WU Xiaoling, XU Jinzhao, XU Yuanzhi, NING Ke, XIE Qinggang, XU Xiaoxi. Effect of Optimized Thioglycolate Medium on the Growth and Metabolites of Akkermansia muciniphila [J]. FOOD SCIENCE, 2023, 44(18): 183-192. |
[6] | DUAN Hao, YAN Wenjie. Research Progress on Bioactive Components in Gastrodia elata Bl. and Their Biological Activity [J]. FOOD SCIENCE, 2023, 44(17): 332-351. |
[7] | WANG Ling’e, PANG Lidong, LI Yu, LI Hongxuan, DING Yixin, HUANG Yan, QI Xuehe, YE Yaming, MAN Chaoxin, JIANG Yujun. Advances in Research on Postbiotics Regulating Obesity [J]. FOOD SCIENCE, 2023, 44(17): 400-410. |
[8] | ZHOU Jing, CUI Chaolin, YUE Pengwei, LI Xiangyang, ZHENG Yuyan. Effects of Different Heat Treatment Temperatures on Eating Quality of Sweet-Scented Osmanthus Flowers [J]. FOOD SCIENCE, 2023, 44(15): 10-18. |
[9] | SU Yarui, FAN Huixia, MA Yueran, LIANG Lihui, KANG Wenyi, GAO Xiaofeng. Advances in the Antifungal Effects of Plant Essential Oils [J]. FOOD SCIENCE, 2023, 44(13): 281-288. |
[10] | WU Yajian, LIANG Miao, ZHANG Zhimin, WANG Rui, LIU Yuping. Analysis of the Key Odorants in Amomum tsaoko Cobs Treated by Different Enzymes [J]. FOOD SCIENCE, 2023, 44(12): 172-180. |
[11] | WANG Zongmin, BAI Hua, WANG Xinyu, ZHU Lanlan, WANG Yanbo, PENG Lin, LIU Jizhou, WU Xudong, SONG Yuedong, SONG Yuanda. Advances in Research on Functional Substances in Vinegar [J]. FOOD SCIENCE, 2023, 44(11): 196-204. |
[12] | ZENG Wenshen, HUANG Darong, XIE Siwei, DU Bing, LI Pan. Progress in Research on Composition, Structure, Functions and Mechanism of Action of Radix Puerariae Isoflavones [J]. FOOD SCIENCE, 2023, 44(1): 353-361. |
[13] | WU Xin, HUANG Bijun, YAN Fangfang, HUANG Yanchun, LU Qun, DING Shiyong, LIU Rui. Effects of Storage and Processing Methods on Processing Quality and Dietary Polyphenols of Black Rice: A Literature Review [J]. FOOD SCIENCE, 2022, 43(3): 362-370. |
[14] | DONG Conghui, DONG Wenjiang, CHENG Jinhuan, HU Rongsuo, HE Hongyan, CHEN Xiao’ai, LONG Yuzhou, HUANG Jiaxiong, CHEN Gang, CHEN Jianfei. Evolution of Fatty Acid Composition, Volatile Flavors and Bioactive Ingredients of Coffee Oil during Coffee Bean Roasting [J]. FOOD SCIENCE, 2022, 43(24): 210-222. |
[15] | SHANG Weixuan, LIU Lu, LEI Suzhen, ZHENG Baodong, ZHANG Yi, ZENG Hongliang. Synergistic Effect of Lotus Seed Resistant Starch and Sodium Lactate on Intestinal Flora and Metabolism in Rats [J]. FOOD SCIENCE, 2022, 43(17): 12-23. |
Viewed | ||||||
Full text |
|
|||||
Abstract |
|
|||||