Research Progress on Immunomodulatory Mechanisms and Applications of Flammulina velutipes Polysaccharides

Abstract

Abstract: Flammulina velutipes polysaccharide (FVP) is one of the major active components of Flammulina velutipes, exhibiting prominent immunomodulatory, anti-inflammatory, antioxidant and antitumor activities. In this paper, the extraction and purification processes as well as the fine structural characteristics of FVP were systematically summarized, and its molecular immunomodulatory mechanisms were emphatically analyzed from five dimensions, namely "immune organs-immune cells-pattern recognition receptors-signaling pathways-intestinal microecology". Meanwhile, the structure-activity relationship of FVP was deeply discussed, and its application potential in the fields of food, medicine, daily chemicals and agriculture was prospected, aiming to provide scientific references for the high-value development of FVP.

Key words: Flammulina velutipes, polysaccharide, immunomodulatory, structure-activity relationship, applications

CLC Number:

Changyang MA. Research Progress on Immunomodulatory Mechanisms and Applications of Flammulina velutipes Polysaccharides[J]. FOOD SCIENCE.

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