Abstract: The Ca2+ signaling pathway include two Ca2+-dependent signaling pathways, calcineurin (CaN) and calmodulin kinase (CaMK), whose activation can promote the transition from fast to slow muscle fibers. This review summarizes the structures and mechanism of action of the CaN and CaMK signaling pathways, the major factors affecting the regulation of the Ca2+ signaling pathway, the role of the Ca2+ signaling pathway in the transformation of muscle fiber types and its relationship with meat quality. Future research directions are also proposed. Hopefully, this review will provide a theoretical basis for improving meat quality through genetic and nutritional approaches.

Key words: CaN signaling pathway, CaMK signaling pathway, muscle fiber type transformation, meat quality