利用超高压技术提取补骨脂中补骨脂素和异补骨脂素

doi:10.7506/spkx1002-6630-201120009

食品科学 ›› 2011, Vol. 32 ›› Issue (20): 39-43.doi: 10.7506/spkx1002-6630-201120009

利用超高压技术提取补骨脂中补骨脂素和异补骨脂素

余平1，刘长姣1,2，乔春峰3，张守勤2,*

1.吉林工商学院食品工程分院 2.吉林大学生物与农业工程学院 3.香港赛马会中药研究院

出版日期:2011-10-25 发布日期:2011-10-12
基金资助:
国家自然科学基金面上基金项目(30472135)

Application of Ultra High Pressure Technology in Extraction of Psoralen and Isopsoralen from Fructus Psoraleae

YU Ping1，LIU Chang-jiao1,2，QIAO Chun-feng3，ZHANG Shou-qin2,*

(1. Branch of Food Engineering, Jilin Business and Technology College, Changchun 130062, China； 2. College of Biological and Agricultural Engineering, Jilin University, Changchun 130025, China； 3. Institute of Chinese Medicine, Hong Kong Jockey Club, Hong Kong 999077, China)

Online:2011-10-25 Published:2011-10-12

摘要/Abstract

摘要： 补骨脂是我国用于生产各种保健品的传统原料之一，其主要活性成分为补骨脂素和异补骨脂素。本实验通过回流提取法和超高压提取法提取补骨脂中补骨脂素和异补骨脂素的对比实验，证明超高压提取法优于回流提取法。通过均匀试验设计优化超高压提取补骨脂素和异补骨脂素的提取工艺，得到补骨脂素最优提取工艺条件为：压力100MPa，乙醇体积分数 53%，液固比90:1(mL/g)，提取时间3min；异补骨脂素的最优提取工艺条件为：压力100MPa，乙醇体积分数 55%，液固比90:1(mL/g)，提取时间3min。实验证明应用超高压提取法可以实现补骨脂素和异补骨脂素的常温、快速提取，为其在保健品和功能性食品中的应用提供高效的生产方法。

关键词: 超高压技术, 补骨脂, 补骨脂素, 异补骨脂素

Abstract: Fructus Psoraleae is one of the most popular raw materials for health products in China. The major bioactive components of Fructus Psoraleae are psoralen and isopsoralen. In the present work, ultra high pressure extraction (UHPE) was used to extract psoralen and isopsoralen from Fructus Psoraleae and compared with the reflux extraction. We found that UHPE resulted in higher yields of psoralen and isopsoralen than the refulx extraction. Using a uniform design, the optimum UHPE conditions including pressure, ethanol concentration, liquid-to-solid raio (mL/g) and extraction time were determined to be 100 MPa, 53%, 90:1 and 3 min for psoralen and 100 MPa, 55%, 90:1 and 3 min for isopsoralen, respectively. UHPE proved to enable normal temperature and rapid extraction of psoralen and isopsoralen, thereby providing an efficient production approach for applying psoralen and isopsoralen in health products and functional products.

Key words: ultra high pressure extraction, Fructus Psoraleae, psoralen, sopsoralen

中图分类号:

R284.2

余平，刘长姣，乔春峰，张守勤. 利用超高压技术提取补骨脂中补骨脂素和异补骨脂素[J]. 食品科学, 2011, 32(20): 39-43.

YUPing，LIUChang-jiao，QIAOChun-feng，ZHANGShou-qin. Application of Ultra High Pressure Technology in Extraction of Psoralen and Isopsoralen from Fructus Psoraleae[J]. FOOD SCIENCE, 2011, 32(20): 39-43.

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利用超高压技术提取补骨脂中补骨脂素和异补骨脂素

Application of Ultra High Pressure Technology in Extraction of Psoralen and Isopsoralen from Fructus Psoraleae

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