食品科学 ›› 2021, Vol. 42 ›› Issue (5): 305-313.doi: 10.7506/spkx1002-6630-20200228-326

• 专题论述 • 上一篇    下一篇

植物多酚与肠道微生物群的相互作用及其对代谢性疾病影响的研究进展

赵媚,常凌,宋泽和,贺喜   

  1. (湖南农业大学动物科学技术学院,饲料安全与高效利用教育部工程研究中心,湖南家禽安全生产工程技术研究中心,湖南畜禽安全生产协同创新中心,湖南 长沙 410128)
  • 出版日期:2021-03-15 发布日期:2021-03-29
  • 基金资助:
    国家重点研发计划政府间国际科技创新合作重点专项(2018YFE0101700); 国家重点研发计划项目(2017YFD0500506);湖南农业大学“双一流”建设项目(SYL201802015)

Interactions between Plant Polyphenols and Intestinal Microbiota and Their Effects on Metabolic Diseases

ZHAO Mei, CHANG Ling, SONG Zehe, HE Xi   

  1. (Engineering Research Center of Feed Safety and Efficient Utilization of China Ministry of Education, Hunan Engineering Research Center of Poultry Production Safety, Hunan Co-innovation Center of Animal Production Safety, College of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, China)
  • Online:2021-03-15 Published:2021-03-29

摘要: 肠道微生物群参与由胰岛素抵抗、高血糖、血脂异常、中心性肥胖和高血压等组成的代谢综合征的发展,进一步导致代谢性疾病的发生。而植物多酚可以促进肠道微生物群中有益菌的生长,间接减少致病菌的数量。并且肠道微生物群能够将高分子质量的植物多酚代谢为更具生物活性的代谢物以提高其生物利用度。本文综述了植物多酚与肠道微生物群两者之间的相互作用及它们对代谢性疾病的影响,为植物多酚的利用提供参考。

关键词: 植物多酚;肠道微生物群;代谢性疾病;代谢综合征;肥胖

Abstract: The intestinal microbiota is involved in the development of metabolic syndromes including insulin resistance, hyperglycemia, dyslipidemia, central obesity and hypertension, which can progress into metabolic diseases. Plant polyphenols can promote the growth of beneficial intestinal bacteria and indirectly reduce the number of pathogenic bacteria. Moreover, the intestinal microbiota can metabolize high-molecular-mass plant polyphenols into metabolites with stronger bioactivity, improving their bioavailability. The interaction between plant polyphenols and the intestinal microbiota and their effects on metabolic diseases are reviewed in this paper, which will provide a reference for the utilization of plant polyphenols.

Key words: plant polyphenols; intestinal microbiota; metabolic diseases; metabolic syndromes; obesity

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