食品科学 ›› 2023, Vol. 44 ›› Issue (7): 240-249.doi: 10.7506/spkx1002-6630-20220504-028

• 专题论述 • 上一篇    

界面工程设计调控油脂基乳液递送体系中脂溶性营养素生物利用率的研究进展

张盈铢,胡俊杰,李斌,刘石林,李艳   

  1. (华中农业大学食品科学技术学院,环境食品学教育部重点实验室,湖北省功能食品工程研究中心,湖北 武汉 430070)
  • 发布日期:2023-04-25
  • 基金资助:
    国家自然科学基金面上项目(31972976)

Research Advances in Interface Engineering Design to Regulate Bioavailability of Lipophilic Nutrients Encapsulated in Lipid-based Emulsion Delivery Systems

ZHANG Yingzhu, HU Junjie, LI Bin, LIU Shilin, LI Yan   

  1. (Key Laboratory of Environmental Correlative Dietology, Ministry of Education, Hubei Functional Food Engineering Research Center, College of Food Science and Technology, Huazhong Agricultural University, Wuhan 430070, China)
  • Published:2023-04-25

摘要: 膳食补充已日渐成为维持人类身体健康的重要干预手段。随着高通量筛选技术的发展,越来越多的营养素被挖掘出来。但很多营养素为脂溶性营养素,其水溶性低、稳定性差、生物利用率低。为此,脂溶性营养素递送体系的设计与开发受到了广泛关注。其中乳液递送体系独具特色,且已被证实能有效改善营养素生物利用率。依据乳液中两相界面的特点,本文综述了油脂基乳液递送体系的界面工程(包括简单界面、复杂界面)对所含脂溶性营养素生物利用率的调控,为改善脂溶性营养素生物效价提供参考。

关键词: 乳液;界面;营养素;消化;生物利用率

Abstract: Dietary supplementation has increasingly become an important interventional strategy to maintain human health. With the development of high-throughput screening technology, more and more nutrients have been discovered. However, many nutrients are characterized by high lipophilicity, poor water solubility, poor stability and low bioavailability. Hence, the design and development of delivery systems for lipophilic nutrients have received extensive attention. Emulsion-based delivery systems have been reported to effectively improve bioavailability of lipophilic nutrients. According to the characteristics of the two-phase interface in emulsions, this paper aims to review the regulation of the interface design of lipid-based emulsions (including simple and complex interfaces) on the bioavailability of lipophilic nutrients for the purpose of providing a reference for improving the bioavailability of lipophilic nutrients.

Key words: emulsions; interface; nutrients; digestion; bioavailability

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