食品科学 ›› 2023, Vol. 44 ›› Issue (19): 250-269.doi: 10.7506/spkx1002-6630-20220815-171

• 专题论述 • 上一篇    

Fe3O4磁性荧光传感器检测真菌毒素的研究进展

贺文,郝丽坤,刘玮,李宁   

  1. (滨州医学院公共卫生与管理学院,山东 烟台 264003)
  • 发布日期:2023-11-07
  • 基金资助:
    国家自然科学基金青年科学基金项目(81902161)

Research Progress on Fe3O4 Magnetic and Fluorescent Sensor for the Detection of Mycotoxins

HE Wen, HAO Likun, LIU Wei, LI Ning   

  1. (School of Public Health and Management, Binzhou Medical University, Yantai 264003, China)
  • Published:2023-11-07

摘要: 真菌毒素能够通过被污染的食物进入人体并在人体内富集,对人体危害巨大。针对真菌毒素污染,应建立起快速、灵敏、准确、有效的检测方法。随着科学技术的进步,各种类型的生物传感器不断发展,其中磁性荧光双功能生物传感器兼具磁性与荧光特性,可对目标物产生灵敏快速的光学响应,在生物检测领域得到广泛应用。本文主要综述近年来Fe3O4磁性纳米颗粒与有机荧光材料、量子点、上转换纳米粒子、金属纳米簇、荧光碳纳米材料相结合的生物传感器在真菌毒素检测领域的研究进展,并对其未来发展进行展望,以期为Fe3O4磁性荧光传感器后续的研究与应用提供参考。

关键词: 磁性纳米材料;荧光传感器;生物检测;真菌毒素

Abstract: Mycotoxins can enter and accumulate in the human body through contaminated foods, which is extremely harmful to human health. A rapid, sensitive, accurate and effective method is needed to detect mycotoxin contamination. With the advancement of science and technology, various types of biosensors have been continuously developed. Among them, magnetic and fluorescent sensors can produce sensitive and fast optical responses to the target compounds. This dual-function sensor has been widely used in the field of biological detection. This article reviews the application and future prospects of biosensors combining Fe3O4 magnetic nanoparticles with organic fluorescent materials, quantum dots, up-conversion nanoparticles, metal nanoclusters or fluorescent carbon nanomaterials in the detection of mycotoxins. This review is expected to provide a reference for further research and application of Fe3O4 magnetic and fluorescent sensors.

Key words: magnetic nanoparticles; fluorescence sensor; biological detection; mycotoxins

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