食品科学 ›› 2023, Vol. 44 ›› Issue (21): 359-376.doi: 10.7506/spkx1002-6630-20221028-293

• 专题论述 • 上一篇    

Omega-3多不饱和脂肪酸对运动性骨骼肌损伤修复的促进作用及相关机制研究进展

杨思梦, 贺庆, 石丽君, 吴迎   

  1. (1.北京体育大学运动人体科学学院,北京 100084;2.艾兰得健康控股有限公司,上海 200120)
  • 发布日期:2023-12-13
  • 基金资助:
    横向联合项目(20191413)

Advances in Understanding the Role of Omega-3 Polyunsaturated Fatty Acids in Promoting Recovery from Exercise-Induced Muscle Injury and Its Underlying Mechanism

YANG Simeng, HE Qing, SHI Lijun, WU Ying   

  1. (1. Sport Science School, Beijing Sport University, Beijing 100084, China; 2. Aland Health Holding Co., Ltd., Shanghai 200120, China)
  • Published:2023-12-13

摘要: Omega-3(ω-3)多不饱和脂肪酸(polyunsaturated fatty acids,PUFAs)是生命活动不可缺少的一种脂肪酸,且机体自身不能合成,必须从食物供给中获得。ω-3 PUFAs在防治慢病中的作用已被广泛证实,近年来,越来越多的研究发现其可促进运动性骨骼肌损伤(exercise-induced muscle damage,EIMD)的修复,但相关机制尚未完全明了。本文通过对ω-3 PUFAs与EIMD的相关报道进行梳理,综述了不同剂量ω-3 PUFAs促EIMD修复的外在功效和内在可能机制。其促EIMD修复机制包括激活肌卫星细胞的肌源性修复,增强骨骼肌细胞质膜修复,提升抗炎、抗氧化作用等,本文可为从运动营养角度不断深入探究促EIMD修复的相关理论与实践提供新思路。

关键词: Omega-3多不饱和脂肪酸;运动性骨骼肌损伤;肌卫星细胞;质膜修复;抗炎;抗氧化

Abstract: Omega-3 (ω-3) polyunsaturated fatty acids (PUFAs) are essential fatty acids for life activities, which cannot be synthesized by the body itself, and must be obtained from food. The role of ω-3 PUFAs in the prevention and treatment of chronic diseases has been widely demonstrated. In recent years, more and more studies have found that ω-3 PUFAs can promote recovery from exercise-induced muscle damage (EIMD), but the mechanism is not fully clarified. Therefore, in this paper, studies on the efficacy and mechanism of action of different doses of ω-3 PUFAs in promoting recovery from EIMD are reviewed. The underlying mechanism involves activating myogenic repair of myosatellite cells, enhancing plasma membrane repair of skeletal muscle cells, and increasing anti-inflammatory and antioxidant activity. This review should provide new ideas for further exploring the theory and practice of promoting recovery form EIMD from the perspective of sports nutrition.

Key words: omega-3 polyunsaturated fatty acids; exercise-induced muscle damage; myosatellite cells; plasma membrane repair; anti-inflammatory; antioxidant

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