食品科学 ›› 2025, Vol. 46 ›› Issue (10): 325-339.doi: 10.7506/spkx1002-6630-20240920-155

• 专题论述 • 上一篇    下一篇

膳食脂质体外消化过程中的自组装结构研究进展

甘婉玲,苏巍,王英,刘小莉,周剑忠,范琳琳   

  1. (1.江苏省农业科学院农产品加工研究所,江苏 南京 210014;2.江苏大学食品与生物工程学院,江苏 镇江 212000)
  • 出版日期:2025-05-25 发布日期:2025-05-07
  • 基金资助:
    国家自然科学基金青年科学基金项目(32202038)

Research Progress on the Formation of Self-Assembled Structures during in Vitro Lipid Digestion

GAN Wanling, SU Wei, WANG Ying, LIU Xiaoli, ZHOU Jianzhong, FAN Linlin   

  1. (1. Institute of Agri-products Processing, Jiangsu Academy of Agricultural Sciences, Nanjing 210014, China; 2. College of Food and Biological Engineering, Jiangsu University, Zhenjiang 212000, China)
  • Online:2025-05-25 Published:2025-05-07

摘要: 脂质是人体需要的重要营养物质之一,在供给人体能量方面起着重要作用。脂质在消化过程中的产物会形成不同的自组装结构,如乳液、囊泡、胶束、溶致液晶等,这些结构是递送活性营养物质的重要载体,不仅影响脂质自身代谢产物的消化代谢,同时也影响营养物质的递送和吸收。本文综述脂质的消化过程及产物,重点论述其形成的自组装结构及这些结构变化对活性物质的肠道递送和生物可及性的潜在影响。了解膳食脂质的消化及其产物自组装结构有助于认识脂质在消化过程中对营养物质尤其是疏水成分的递送作用,同时可为新型自组装营养递送系统的开发提供参考。

关键词: 脂质消化;自组装结构;营养递送;生物可及性

Abstract: Lipids are one of the important nutrients needed by the human body and play an important role in supplying energy to the body. Different self-assembled structures such as emulsions, liposomes/vesicles, micelles, lyotropic liquid crystals are easily formed during lipid digestion. These structures are important carriers for delivering active nutrients, which not only affect the digestion and metabolism of lipids, but also influence the delivery and absorption of nutrients. This article reviews the digestion process and metabolites of lipids, focusing on the self-assembled structures of lipids and the potential influence of their changes on the intestinal delivery and bioaccessibility of active substances. Understanding the digestion process of dietary lipids and the self-assembly structures of their metabolites is helpful to understand the role of lipids in delivering nutrients, especially hydrophobic ones, during the digestion process, providing a reference for new self-assembled systems for nutrient delivery.

Key words: lipid digestion; self-assembled structure; nutrient delivery; bioaccessibility

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