食品科学 ›› 2005, Vol. 26 ›› Issue (8): 526-529.

• 专题论述 • 上一篇    下一篇

抗菌肽抗菌机理的研究现状及趋势

 王军, 庞广昌   

  1. 天津商学院生物工程系
  • 出版日期:2005-08-15 发布日期:2011-09-19

Review on the Current Status and Development Trend of Mechanism of Antimicrobial peptides

 WANG  Jun, PANG  Guang-Chang   

  1. The Department of Bioengineering, Tianjin University of Commerce
  • Online:2005-08-15 Published:2011-09-19

摘要: 抗菌肽广泛存在于从原核生物到人类的各个物种有机体和机体组织中,一般都具有广谱抗菌活性,其抗菌机理近年来成为国内外研究的热点。本文综述了抗菌肽及其抗菌机理研究的最新进展,阐述了先天免疫在哺乳动物来源抗菌肽发挥抗菌活性时的重要作用,并对抗菌肽的开发应用前景进行了展望。

关键词: 抗菌肽, 抗菌机理, 研究进展

Abstract: Antimicrobial peptides have been discovered from tissues and organisms representing virtually every kingdom and phylum, ranging from prokaryotes to humans. Generally antimicrobial peptides have the broad spectrum antibacterial activity, its antibacterial mechanism became the domestic and foreign research hot spot in recent years. This article summarized the newest progress whicht hea ntibacterial peptide andi ts antibacterialm echanisms tudies, elaboratedt hev italr oleo ft he innatei mmunity when the antibacterial peptide, which separated from mammal, display antibacterial activity, and has carried on the forecast to thea ntibacterialp eptided evelopment applicationp rospect.

Key words: antibacterial peptide, antibacterial mechanism, review, prospect