食品科学 ›› 2025, Vol. 46 ›› Issue (12): 1-13.doi: 10.7506/spkx1002-6630-20241231-274

• 专家约稿 •    下一篇

类器官在食品科学研究中的应用进展

马爱进,白如进,周军君,贾英民   

  1. (北京工商大学食品与健康学院,北京 100048)
  • 出版日期:2025-06-25 发布日期:2025-05-23
  • 基金资助:
    “十四五”国家重点研发计划重点专项(2022YFD1600402)

A Review on the Application of Organoids in Food Science Research

MA Aijin, BAI Rujin, ZHOU Junjun, JIA Yingmin   

  1. (School of Food and Health, Beijing Technology and Business University, Beijing 100048, China)
  • Online:2025-06-25 Published:2025-05-23

摘要: 类器官是一种三维细胞培养物,具备器官的一些关键特性,在食品科学研究中的应用日益受到重视。本文介绍肠道、肝脏和脑这3 种主要类器官的构建和功能鉴定研究现状,阐述肠、肝脏、脑等类器官在食品领域的应用进展,并探讨类器官与芯片技术、微流控技术等前沿技术整合应用的前景,分析食品研究中类器官模型应用面临的挑战及发展方向,旨在为推进类器官在食品科学领域的研究及应用提供参考。

关键词: 类器官;食品;三维培养;应用;发展方向

Abstract: Organoids are three-dimensional cell cultures that possess some key properties of organs, and their application in food science research has been increasingly emphasized. This paper introduces the current status of the construction and functional characterization of three major organoids, namely, intestinal, liver and brain organoids, describes recent progress in the application of intestinal, liver and brain organoids in the field of food science, discusses future prospects for the integrated application of organoids with cutting-edge technologies such as microarray technology and microfluidics, and analyzes the challenges and future directions for the application of organoid models in food science. We hope that this review can provide a reference for promoting the research and application of organoids in the field of food science.

Key words: organoids; food; three-dimensional culture; application; development directions

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