食品科学 ›› 2009, Vol. 30 ›› Issue (1): 242-245.doi: 10.7506/spkx1002-6630-200901057

• 营养卫生 • 上一篇    下一篇

富硒益生菌对小鼠生产性能、抗氧化力、肠道菌群的影响

杨家军,黄克和* ,赵治平,卫程武,吴显实   

  1. 南京农业大学动物医学院
  • 收稿日期:2008-01-25 修回日期:2008-05-07 出版日期:2009-01-01 发布日期:2010-12-29
  • 通讯作者: 杨家军 E-mail:yjj1984112@163.com
  • 基金资助:

    国家自然科学基金项目(30671547);广东省教育部产学研科技合作项目(2006d90204008)

Effects of Selenium-enriched Probiotics on Growth Performance, Anti-oxidant Status and Resident Intestinal Flora in Kunming Mice

YANG Jia-jun,HUANG Ke-he*,ZHAO Zhi-ping,WEI Cheng-wu,WU Xian-shi   

  1. (College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, China)
  • Received:2008-01-25 Revised:2008-05-07 Online:2009-01-01 Published:2010-12-29
  • Contact: YANG Jia-jun E-mail:yjj1984112@163.com

摘要:

将75 只昆明系雄性小鼠,随机均分为5 组(n=15):对照组、富硒益生菌组、益生菌组、亚硒酸钠组和有机硒益生素组,实验期为30d。比较了各处理组中小鼠增重、抗氧化力(全血GPX 和血浆SOD 酶活性及血浆MDA含量)、全血硒含量、肌肉中硒含量及盲肠中的三种固有菌数。结果表明,30d 后富硒益生菌对小鼠的增重影响显著高于其他组;于第15d 各补硒组抗氧化力、血液硒含量显著升高,30d 后无机硒和有机硒组中肌肉的硒含量显著高于对照组但低于富硒益生菌;15d 后补充益生菌的小鼠肠道内菌群结构得到改善,其固有菌群(乳酸菌、酵母菌)显著高于其他组。富硒益生菌对小鼠的各检测指标的影响显著优于其他组。

关键词: 硒, 益生菌, 小鼠

Abstract:

75 male Kuming mice were randomly divided into control, sodium selenite, organic-selenium (Se) with inactivated probiotics, Se-enriched probiotics or probiotics groups (n=15) in the experiment, and all the mice were fed for 30 days. The growth performance, Se concentration in blood and skeletal muscle, anti-oxidation status and resident intestinal flora of each treatment group were studied to compare their differences. The results indicated that the body weights of mice fed Se-enriched probiotics diet are higher than those of others after fed for 30 days. Anti-oxidation status and Se concentration in blood increase when Se is supplemented; however Se content in skeletal muscle of the mice fed inorganic or organic Se is lower than that of mice fed selenium-enriched probiotics. The composition of resident bacterial flora in gut is enhanced when mice are fed with probiotics. In conclusion, the measured indexes of mice fed selenium-enriched probiotics are markedly better than those of other groups.

Key words: selenium, probiotics, mouse

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