大豆植物提取物的抗炎和镇痛作用研究

食品科学 ›› 2007, Vol. 28 ›› Issue (11): 533-536.

大豆植物提取物的抗炎和镇痛作用研究

张风光, 彭欣莉, 曲红光, 昌友权, 魏凤辉

吉林工程技术师范学院生物与食品工程系；吉林大学医学部；白城高等医学专科学校吉林长春130052；吉林长春130052；吉林长春130021白城高等医学专科学校；吉林白城137000；

出版日期:2007-11-15 发布日期:2011-11-22

Study on Effects of Soybean Plant Extract on Anti-inflammatory and Analgesic

ZHANG Feng-Guang, PENG Xin-Li, QU Hong-Guang, CHANG You-Quan, WEI Feng-Hui

1.Department of Biology and Food Science, Jilin Teacher’s Institute of Engineering and Technology, Changchun 130052, China; 2.Faculty of Medicine, Jilin University, Changchun 130021, China; 3.Baicheng Higher Medical College, Baicheng 137000, China

Online:2007-11-15 Published:2011-11-22

摘要/Abstract

摘要： 目的:研究大豆植物提取物的抗炎、镇痛作用。方法:采用小鼠耳廓肿胀法、大鼠卵白蛋白致足肿胀法、大鼠棉球肉芽肿法、小鼠热板法和小鼠扭体法。结果:大豆植物提取物能抑制二甲苯引起的小鼠耳廓炎性肿胀和大鼠卵白蛋白性足肿胀,并能减轻大鼠棉球肉芽肿重量,说明大豆植物提取物有明显的抗炎作用。镇痛试验表明,大豆植物提取物能显著提高热板试验小鼠的痛阈,有效抑制冰醋酸引起的小鼠扭体反应次数。结论:大豆植物提取物具有抗炎和镇痛作用。

关键词: 大豆植物提取物, 抗炎作用, 镇痛作用

Abstract: Objective: To study the anti-inflammatory and analgesic effects of soybean plant extracts. Method: Appling to ear swelling of mice, paw edema induced by ovalbumin in rats, cotton granuloma in rats, hot plate in mice and writhing test in mice. Results: Soybean plant extracts can inhibit ear inflammation induced by xylene in mice and paw swelling induced by ovalbumin in rats, and cotton rats can reduce the quality of cotton granuloma in rats, it is demonstrated that soybean plant extract has anti- inflammatory effect clearly. Analgesic tests showed that the soybean plant extracts can significantly improve the pain threshold of mice in the hot plate test, and effective inhibition writhing response frequency induced by acetic acid. Conclusion: Soybean plant extract has anti-inflammatory and analgesic effects.

Key words: soybean plant extract, anti-inflammatory, analgesic effect

张风光, 彭欣莉, 曲红光, 昌友权, 魏凤辉. 大豆植物提取物的抗炎和镇痛作用研究[J]. 食品科学, 2007, 28(11): 533-536.

ZHANG Feng-Guang, PENG Xin-Li, QU Hong-Guang, CHANG You-Quan, WEI Feng-Hui. Study on Effects of Soybean Plant Extract on Anti-inflammatory and Analgesic[J]. FOOD SCIENCE, 2007, 28(11): 533-536.

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