食品科学 ›› 2004, Vol. 25 ›› Issue (12): 172-174.

• 营养卫生 • 上一篇    下一篇

不同水解度酪蛋白酶解产物对小鼠脾淋巴细胞增殖调节活性的比较

 毛学英, 南庆贤, 李莹辉, 宋锦平, 钟萍   

  1. 北京大学环境工程系水沙科学教育部重点实验室,中国农业大学食品科学与营养工程学院,航天医学工程研究所
  • 出版日期:2005-12-15 发布日期:2011-10-24

Study on Effects of Casein Hydrolysates of Different DH on Mouce Spleen Cells Lymphopoliferation Activity and IL-2 Release

 MAO  Xue-Ying, NAN Qing-Xian , LI  Ying-Hui, SONG  Jin-Ping, ZHONG  Ping   

  1. 1.Department of Environmental Engineering,Peking University;2.College of Food Science and Nutritional Engineering,CAU;3.Intitute of Space Medico-Engineering
  • Online:2005-12-15 Published:2011-10-24

摘要: 以小鼠的脾淋巴细胞作为供试细胞和效应细胞,采用MTS法、ELISA法分别测定了不同水解度酪蛋白胰蛋白酶酶解产物(A、B和C样的水解度分别为9.74%、18.54%和24.02%)对小鼠脾淋巴细胞增殖活性、白细胞介素-2(IL-2)生成量的影响,结果显示B样和C样对小鼠脾淋巴细胞增殖和IL-2生成有促进作用,而A样抑制小鼠脾淋巴细胞增殖和IL-2生成。

关键词: 酪蛋白, 酶解产物, 水解度, 免疫调节活性

Abstract: This research studied the effect of casein hydrolysates of different DH (the DH of A, B, and C were 9.74%, 18.54%, and 24.02% respectively) on the lymphoproliferation activity and IL-2 release of mouse spleen cells. The results showed that sample B and C could promote lymphoproliferation activity and IL-2 release, while sample A had inhibitory effect on both.

Key words: casein, enzymatic hydrolysate, degree of hydrolysis (DH), immunoregulatory activity