Fe3O4@Si-C8/C18复合磁性纳米材料的制备及在兽药净化中的应用

食品科学 ›› 2012, Vol. 33 ›› Issue (18): 108-112.

Fe3O4@Si-C8/C18复合磁性纳米材料的制备及在兽药净化中的应用

张恒1，阳承利2，吕敬章1，汤慕瑾1，刘启颂2，万志刚1，谢丽琪1，岳振峰1，李丽苏1

1.深圳出入境检验检疫局 2.北京大学深圳研究生院

收稿日期:2011-07-12 修回日期:2012-07-22 出版日期:2012-09-25 发布日期:2012-09-07
通讯作者: 张恒 E-mail:yzhangheng@163.com
基金资助:
国家质检总局科技计划项目

Preparation of Compound Magnetic Nanoparticle Fe3O4@Si-C8/C18 and Its Application in Purification of Veterinary Drugs

Received:2011-07-12 Revised:2012-07-22 Online:2012-09-25 Published:2012-09-07

摘要/Abstract

摘要： 将Fe3O4@Si-C8/C18复合磁性纳米材料应用于食品安全中的兽药净化领域，采用共沉淀法制备磁性纳米前躯体，并在乙醇相中进行表面硅化处理及(辛基三甲氧基硅烷)C8/(十八烷基三甲氧基硅烷)C18表面修饰，经透射电镜、X射线、磁性能分析、红外光谱等手段对所制备的复合磁性纳米进行表征，所制备的磁性纳米大小均匀，粒径在100～1000nm范围内可调，经多重修饰后的Fe3O4@Si-C8/C18复合磁性纳米材料其磁性强度没有明显降低，并具有表面富集功能。为考察这种磁性纳米材料在兽药提取中的应用，选取豆芽中氯霉素残留的净化来进行初步研究，结果表明所制备的复合型磁性纳米材料在小分子净化富集中展现出广阔的应用价值，尤其在食品安全领域。

关键词: 复合磁性纳米, C8/C18, 兽药净化

Abstract: In this paper, we first applied compound magnetic nanoparticle Fe3O4@Si-C8/C18 to purify veterinary drugs, and co-precipitation method was employed to synthesize the precursor of magnetic nanoparticles. The surface of nanoparticle precursor was silicified in ethanol and modified with C8 (octyltrimethoxysilane)/C18 (octadecyltrimethoxysilane) to prepare composite magnetic nanoparticle Fe3O4@Si-C8/C18. The compound magnetic nanoparticles were characterized by TEM, X-ray, magnetic performance analysis, and infrared spectroscopy. These compound magnetic nanoparrticles revealed high uniformity with adjustable particle diameters of 100－1000 nm. Therefore, after several layer-by-layer modifications, the compound magnetic nanoparticle revealed the same magnetic intensity as its original precursor. In order to validate their application possibility in the purification of veterinary drugs, purification of chloramphenicol residues in bean sprout was conducted using these magnetic nanoparticles. The results demonstrated that these compound magnetic nanoparticles had extensive application value for the purification and enrichment of micromolecules, especially in the field of food safety.

Key words: compound magnetic nanoparticle, C8/C18, purification of veterinary drug

中图分类号:

S859.84

张恒1，阳承利2，吕敬章1，汤慕瑾1，刘启颂2，万志刚1，谢丽琪1，岳振峰1，李丽苏1. Fe3O4@Si-C8/C18复合磁性纳米材料的制备及在兽药净化中的应用[J]. 食品科学, 2012, 33(18): 108-112.

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