关键词: 抗性淀粉, 胃损伤, HCl-乙醇诱导, 血清IL-6细胞因子, 血清TNF-&alpha, 细胞因子

Abstract:

Rats were fed on a basal diet supplemented different levels of high-amylose corn starch (Hylon Ⅶ) to explore the
effect of resistant starch on hydrochloric acid/ethanol-induced gastric lesions in rats using ELISA and reverse transcription-
PCR (RT-PCR). The results showed that 10% RS2, 15% RS2 and 20% RS2 groups could reduce serum IL-6 and TNF-α
levels and gastric lesion area, and significantly increase the inhibition rate of gastric lesions when compared with the stomach
injury control group. In addition, these three concentrations of RS2 could decrease the secretion of gastric juice, and increase
gastric pH. These results suggest that RS2 at the three concentration levels has a significant preventive effect on hydrochloric
acid/ethanol-induced gastric lesions in rats and 20% RS2 is the most effective level.

Key words: resistant starch, gastric lesions, hydrochloric acid/ethanol-induced, serum IL-6, serum TNF-α