食品科学 ›› 2021, Vol. 42 ›› Issue (17): 267-274.doi: 10.7506/spkx1002-6630-20200705-060

• 专题论述 • 上一篇    下一篇

真菌毒素多重检测技术研究进展

陈瑞鹏,孙云凤,霍冰洋,秦英凯,李双,梁俊,周焕英,高志贤   

  1. (1.军事科学院军事医学研究院环境医学与作业医学研究所,天津 300050;2.天津科技大学 省部共建食品营养与安全国家重点实验室,天津 300457)
  • 发布日期:2021-09-29
  • 基金资助:
    “十三五”国家重点研发计划重点专项(2018YFC1603500);广东省重点领域研发计划项目(2019B020211001)

Progress in Multiple Detection Technologies for Mycotoxins

CHEN Ruipeng, SUN Yunfeng, HUO Bingyang, QIN Yingkai, LI Shuang, LIANG Jun, ZHOU Huanying, GAO Zhixian   

  1. (1. Institute of Environmental Medicine and Operational Medicine, Academy of Military Medical Sciences, Academy of Military Sciences, Tianjin 300050, China; 2. State Key Laboratory of Food Nutrition and Safety, Tianjin University of?Science & Technology, Tianjin 300457, China)
  • Published:2021-09-29

摘要: 真菌毒素分布广、污染重、防控难,从农田到餐桌的全过程均易污染农产品,严重威胁人畜健康和生态环境安全。据统计,农产品真菌毒素的污染中超过75%为多种真菌毒素的混合污染,因此建立高灵敏、高通量的真菌毒素检测技术成为当今食品安全检测领域普遍面临的重大挑战。本文综述了近5 年真菌毒素多重检测技术的研究进展,主要包括高效液相色谱-串联质谱法、免疫层析法、化学比色法、电化学法、化学发光法、荧光法、拉曼光谱法等,分析了这些方法在真菌毒素多重检测中的应用与亟待解决的问题,并对其未来的发展应用前景进行了展望。

关键词: 农产品;真菌毒素;适配体;多重检测

Abstract: Mycotoxins are widely distributed, heavily polluting, and difficult to prevent and control. During the whole process from farm to table, agricultural products are easily polluted by mycotoxins, posing serious threats to human and animal health as well as ecological and environmental safety. According to statistics, more than 75% of mycotoxin contamination in agricultural products is caused by a mixture of multiple mycotoxins. Therefore, establishing a highly sensitive and high-throughput mycotoxin detection technology is a major challenge in the field of food safety testing. This article summarizes the progress in the multiple detection of mycotoxins in the past five years, including high performance liquid chromatography-tandem mass spectrometry, immunochromatography, chemical colorimetry, electrochemistry, chemiluminescence and fluorescence spectroscopy. The applications of these methods in the multiple detection of mycotoxins and the problems to be solved are analyzed, and prospects are discussed.

Key words: agricultural products; mycotoxins; aptamers; multiple detection

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