食品科学 ›› 2022, Vol. 43 ›› Issue (9): 364-372.doi: 10.7506/spkx1002-6630-20210302-017

• 专题论述 • 上一篇    下一篇

乳酸菌代谢低聚果糖/菊粉途径及机理的研究进展

赖鲸慧,祝元婷,陈媛,唐林,陈贵希,李建龙,刘书亮   

  1. (1.四川农业大学食品学院,四川 雅安 625014;2.四川师范大学生命科学学院,四川 成都 610066;3.四川农业大学食品加工与安全研究所,四川 雅安 625014)
  • 出版日期:2022-05-15 发布日期:2022-05-27
  • 基金资助:
    四川省科技厅重点研发项目(2019YFN0110);四川省科技厅应用基础面上项目(2021YJ0274)

Recent Progress in Understanding Metabolic Pathways and Mechanisms of Fructooligosaccharides/Inulin by Lactic Acid Bacteria

LAI Jinghui, ZHU Yuanting, CHEN Yuan, TANG Lin, CHEN Guixi, LI Jianlong, LIU Shuliang   

  1. (1. College of Food Science, Sichuan Agricultural University, Ya’an 625014, China;2. College of Life Science, Sichuan Normal University, Chengdu 610066, China;3. Institute of Food Processing and Safety, Sichuan Agricultural University, Ya’an 625014, China)
  • Online:2022-05-15 Published:2022-05-27

摘要: 合生元又称合生素,指益生元与益生菌结合使用的生物制剂(微生态制剂),近年来,越来越多研究表明合生元具有多种益处,益生元和益生菌的选择对其最终效果起着至关重要的作用。低聚果糖和菊粉是合生元中常见的益生元,可被肠道内的乳酸菌选择性吸收,通过促进益生菌增殖的方式来改善机体健康。本文综述了乳酸菌对低聚果糖和菊粉的代谢差异及代谢途径,并从分子水平阐述水解酶、转运系统、调控蛋白的作用机制,以期为探明乳酸菌调控低聚果糖和菊粉的代谢网络提供依据;同时总结了近年来低聚果糖/菊粉合生元的应用,为益生元与益生菌的进一步联用提供参考。

关键词: 乳酸菌;合生元;低聚果糖;菊粉;代谢机制

Abstract: Synbiotics refer to biological agents (probiotics) used in combination with probiotics. In recent years, accumulating studies have reported that synbiotics possess many health benefits. The ef?cacy of symbiotics is affected by the selection of probiotics and prebiotics. Fructooligosaccharides and inulin are commonly used as probiotics, which can be selectively absorbed by probiotics in the intestine and promote the proliferation of probiotics, thereby keeping the host healthy. This paper reviews the differential metabolism and metabolism pathways of fructooligosaccharides (FOS) and inulin by lactic acid bacteria, and summarizes the mechanisms of action of the hydrolases, transport systems, and regulatory proteins at the molecular level in order to provide basis for understanding the regulatory mechanism of the metabolic network of FOS and inulin by lactic acid bacteria. Besides, it summarizes the recent applications of synbiotics containing FOS and/or inulin with a view to providing valuable evidence to extend the combined application of prebiotics and probiotics.

Key words: lactic acid bacteria; symbiotics; fructooligosaccharides; inulin; metabolic mechanism

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