超细大豆皮膳食纤维对糖尿病模型小鼠糖耐量的影响

doi:10.7506/spkx1002-6630-201021074

食品科学 ›› 2010, Vol. 31 ›› Issue (21): 329-331.doi: 10.7506/spkx1002-6630-201021074

超细大豆皮膳食纤维对糖尿病模型小鼠糖耐量的影响

肖安红^1,2，陆世广^1,2

1. 武汉工业学院 2. 湖北省农产品加工与转化重点实验室

收稿日期:2010-02-24 出版日期:2010-11-15 发布日期:2010-12-29
通讯作者: 肖安红 E-mail:xiao19630118@sina.com
基金资助:
湖北省自然科学基金项目(2008CDA077)

Effect of Superfine Dietary Fiber from Soybean Bran on Blood Glucose Tolerance in Diabetic Mice

XIAO An-hong1,2，LU Shi-guang1,2

1. Wuhan Polytechnic University, Wuhan 430023, China；
2. Hubei Key Laboratory for Processing and Transformation of Agricultural Product, Wuhan 430023, China

Received:2010-02-24 Online:2010-11-15 Published:2010-12-29
Contact: XIAO An-hong E-mail:xiao19630118@sina.com

摘要/Abstract

摘要：

目的：探讨超细大豆皮膳食纤维对正常和四氧嘧啶致糖尿病模型小鼠糖耐量的影响。方法：对正常和四氧嘧啶致糖尿病模型小鼠灌胃5g/kg bw 超细大豆皮膳食纤维(140～200 目和穿过200 目)后进行血糖耐量实验。结果：与正常对照组比较，正常小鼠两个剂量组的血糖曲线下面积分别减小14.94% 和15.48%，有显著性差异(P ＜ 0.05)，餐后血糖峰值分别降低12.38% 和12.51%；对糖尿病模型小鼠，两个剂量组的血糖曲线下面积分别减小24.05% 和29.68%，有极显著性差异(P ＜ 0.01)，餐后血糖峰值分别降低38.71% 和39.26%。结论：超细大豆皮膳食纤维使正常和糖尿病模型小鼠的糖耐量有显著改善，使餐后血糖峰值及血糖值降低，但大豆皮膳食纤维的粒度差别对正常和糖尿病模型小鼠的血糖耐量和餐后血糖峰值影响差别不明显。

关键词: 超细大豆皮膳食纤维, 粒度, 糖尿病模型小鼠, 糖耐量

Abstract:

Purpose: To explore the effect of superfine dietary fiber from soybean bran on glucose tolerance in diabetic mice. Methods: Glucose tolerance was determined in common and alloxan-induced diabetic mice fed different granular sizes of superfine dietary fiber (140－200 mesh and more than 200 mesh) at a dosage of 5 g/kg bw each day. Results: Compared with the model group, the areas under the blood sugar curve in common mice treated with superfine dietary fiber at two dosages decreased by 14.94% and 15.48% (P < 0.05), and blood sugar peaks in common mice after meal at two dosages decreased by 12.38% and 12.51%. Similarly, compared with the model group, the areas under the blood sugar curve in diabetic mice treated with superfine dietary fiber at two dosages decreased by 24.05% and 29.68% (P < 0.01), and blood sugar peaks in diabetic mice after meal at two dosages decreased by 38.71% and 39.26%. Conclusion: The blood sugar tolerance in common and diabetic mice treated with superfine dietary fiber has an obvious improvement, and blood sugar peaks and blood sugar levels in common and diabetic mice after meal are significantly decreased. However, the granular size of superfine dietary fiber does not exhibit obvious improving effect on blood sugar tolerance and decrease in blood sugar level.

Key words: superfine dietary fiber from soybean bran, granular size, diabetic mice, blood glucose tolerance

中图分类号:

TS214.2

肖安红1,2，陆世广1,2. 超细大豆皮膳食纤维对糖尿病模型小鼠糖耐量的影响[J]. 食品科学, 2010, 31(21): 329-331.

XIAO An-hong1,2，LU Shi-guang1,2. Effect of Superfine Dietary Fiber from Soybean Bran on Blood Glucose Tolerance in Diabetic Mice[J]. FOOD SCIENCE, 2010, 31(21): 329-331.

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超细大豆皮膳食纤维对糖尿病模型小鼠糖耐量的影响

Effect of Superfine Dietary Fiber from Soybean Bran on Blood Glucose Tolerance in Diabetic Mice

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