Abstract:

An analytical method using ion chromatography coupled with tandem mass spectrometry (IC-MS/MS) was developed for the determination of bromate in flour. Samples were dispersed in water, extracted with sonication, and cleaned up with a pre-activated C18 solid-phase extraction cartridge before IC-MS/MS analysis. Recoveries of bromate in flour spiked within the range of 10.0－50.0 μg/kg ranged from 82.1% to 86.6%, with coefficients of variation between 4.5% and 7.3%. The limit of detection was 3μg/kg (RSN ＝ 3). These results suggest that this method is simple, sensitive and precise, and therefore can be used for qualification and quantification of bromate in flour.

Key words: bromate, flour, IC-MS/MS