Abstract:

Effect of Spirulina on learning and memory disturbance on aging mice model induced by D-galactose by gavage was investigated. Following by six-week administration, the ability of learning and memory was assessed by step-down test, dark avoidance test, water-maze spatial localization task. Results indicated that the ability of learning and memory in model group decreases (p＜0.05 or p＜0.01), and this ability is recovered in different degrees following by Spirulina feeding (p＜0.05). In conclusion, Spirulina is favorable for the recovery of learning and memory disturbance in aging mice.

Key words: Spirulina, aging, memory disturbance, improvement