in vivo Anti-tumor Activity of Total Saponins from Asparagus officinalis

doi:10.7506/spkx1002-6630-201013062

FOOD SCIENCE ›› 2010, Vol. 31 ›› Issue (13): 273-275.doi: 10.7506/spkx1002-6630-201013062

• Nutrition & Hygiene • Previous Articles Next Articles

in vivo Anti-tumor Activity of Total Saponins from Asparagus officinalis

SONG Qing1，CHAI Qiu-yan2，ZHANG Li-wei1,*

1. Institute of Molecular Science, Shanxi University, Taiyuan 030006, China ；
2. Shanxi Academy of Medicine and Life Science, Taiyuan 030006, China

Received:2009-11-24 Revised:2010-03-31 Online:2010-07-01 Published:2010-12-29
Contact: ZHANG Li-wei1,* E-mail:lwzhang@sxu.edu.cn

Abstract

Abstract:

The anti-tumor activity and immune regulation activity of total saponins from Asparagus officinalis were investigated by determining tumor weight and immune organ weight. The results indicated that total saponins from Asparagus officinalis had significant dose-dependent inhibitory effects on the growth of sarcoma S180 (S180) and hepatoma H22 (H22) cells implanted into healthy mice. The inhibition rate in high-dose group was 39.53% (P ＜ 0.05) on S180 and 34.81% (P ＜ 0.01) on H22 cells.

Key words: Asparagus officinalis, total saponins, anti-tumor activity

CLC Number:

R730.52

SONG Qing1，CHAI Qiu-yan2，ZHANG Li-wei1,*. in vivo Anti-tumor Activity of Total Saponins from Asparagus officinalis[J]. FOOD SCIENCE, 2010, 31(13): 273-275.

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in vivo Anti-tumor Activity of Total Saponins from Asparagus officinalis

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