Hypoglycemic Effect of Bioactive Components in Mulberry Leaves

doi:10.7506/spkx1002-6630-201107071

FOOD SCIENCE ›› 2011, Vol. 32 ›› Issue (7 ): 323-326.doi: 10.7506/spkx1002-6630-201107071

• Nutrition & Hygiene • Previous Articles Next Articles

Hypoglycemic Effect of Bioactive Components in Mulberry Leaves

XUAN Guang-shan1，PAN Shi-jia1，NAN Ji2

1. College of Chemical Engineering, Qingdao University of Science and Technology, Qingdao 266042, China；
2. International College, Qingdao University of Science and Technology, Qingdao 266061, China

Received:2010-09-07 Revised:2011-02-24 Online:2011-04-15 Published:2011-03-30

Abstract

Abstract: Objective: To explore the hypoglycemic effect of polysaccharides, flavonoids and alkaloids from mulberry leaves. Methods: A mouse model of diabetes was established to explore the effects of mulberry leaf polysaccharides, flavonoids and alkaloids on blood glucose, blood lipid and glucose tolerance. Results: The polysaccharides, flavonoids and alkaloids could obviously decrease blood glucose, improve glucose tolerance, and resist abnormal blood lipid in diabetic mice. The reduction rates of blood glucose in mice administered with mulberry leaf polysaccharides, flavonoids and alkaloids were 14.42%, 27.33% and 37.55%, respectively. Conclusion: Mulberry leaf polysaccharides, flavonoids and alkaloids can prevent and treat diabetes. Mulberry leaf alkaloids have obvious hypoglycemic effect and exhibit better hypoglycemic function than the positive reference substance metformin.

Key words: polysaccharides, flavonoids, alkaloids, hypoglycemic, diabetic mice

CLC Number:

R931.71

XUAN Guang-shan1，PAN Shi-jia1，NAN Ji2. Hypoglycemic Effect of Bioactive Components in Mulberry Leaves[J]. FOOD SCIENCE, 2011, 32(7 ): 323-326.

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Hypoglycemic Effect of Bioactive Components in Mulberry Leaves

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