Abstract: Objective: To analyze chemical constituents of Pseudostellaria heterophylla (Miq.) Pax cultivated in different regions. Methods: The contents of trace elements (Cu, Fe, Zn, Mn, Ca, Mg, Se and Co) were determined by atomic absorption spectrophotometry, saponins and polysaccharide were determined by ultraviolet spectrophotometry, and volatile components were identified by GC-MS. Results: The highest contents of trace elements such as Fe, Mn, Mg, Ca and Co as well as saponins were determined in Pseudostellaria heterophylla (Miq.) Pax cultivated in GuiZhou. The highest contents of trace elements of Zn and Se were observed in Pseudostellaria heterophylla (Miq.) Pax cultivated in Fujian. The contents of Cu and polysaccharide were detected in Pseudostellaria heterophylla (Miq.) Pax cultivated in Zhejiang. Pseudostellaria heterophylla (Miq.) cultivated in different regions had different volatile components. Totally 29, 28 and 25 volatile components were identified in Pseudostellaria heterophylla (Miq.) Pax cultivated in Zhejiang, Guizhou and Fujian. Conclusion: Environment and breed type could effect on the contents of chemical compositions. The soil and climate of Guizhou are suitable for the healthy growth of Pseudostellaria heterophylla (Miq.).

Key words: Pseudostellaria heterophylla (Miq.) Pax, cultivated in different region, chemical compositions