FOOD SCIENCE ›› 2012, Vol. 33 ›› Issue (13): 334-338.doi: 10.7506/spkx1002-6630-201213070

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Research Advances in Allergenrity of Glycosylated Whey Protein

LIULi-bo,SUNDi,LIChun,LIUNing,LIUJing-sheng   

  1. (1. College of Food Science and Engineering, Jilin Agricultural University, Changchun 130118, China ;2. Key Laboratory of Dairy Science, Ministry of Education, College of Food Science, Northeast Agricultural University, Harbin 150030, China)
  • Online:2012-07-15 Published:2012-07-27

Abstract: Bovine milk is nutritious in multiple aspects. It has become the most suitable food source for infants. However, many infants are allergic to bovine milk. Maillard reaction provides a novel method for glacosylation modifications of whey proteins, and has gained extensive attention in the food field. In this paper, the structural characteristics and allergenicity of major milk allergens are summarized. Glycosylation modifications of α-lactalbumin and β-lactoglobulin are also reviewed. Meanwhile, the immunogenicity of whey protein can be reduced by conjugation with saccharides, without destroying its molecular structure and functions.

Key words: α-lactalbumin, β-lactoglobulin, antigenicity, glycosylation

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