Abstract: Objective: To optimize extraction process of chlorogenic acid in burdock root peels by cellulose methods. Methods: The effects of enzyme dosage, material-liquid ratio, extraction temperature, extraction duration and extraction pH on the yield of chlorogenic acid from burdock root peels by single factor and orthogonal tests were explored. Results: The optimal extraction process included cellulose addition amount of 4 mL, extraction temperature of 60 ℃, extraction time of 1.5 h, extraction pH 6.0, and material-liquid ratio of 1:20. Under the optimal extraction conditions, the maximum yield of chlorogenic acid was 1.45%.

Key words: burdock, chlorogenic acid, extraction